CAJ | 학술논문

目的：探讨血脂对乳腺癌远处转移的预测价值。方法选取该院2011年12月至2013年12月诊治的乳腺癌患者115例为观察组，根据癌细胞转移情况分为两组，78例患者未发生癌细胞远处转移为A组，37例患者发生癌细胞远处转移为B 组。选取本院同期健康体检人员115例为对照组。均行血脂相检测。分析血脂与乳腺癌远处转移的关系。结果观察组患者总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL－C）均明显高于对照组，观察组患者高密度脂蛋白胆固醇（HDL－C）明显低于对照组，B组患者 TC、TG、LDL－C 均明显高于原位组，转移组患者HDL－C明显低于A组（P＜0．05）。高TC血症、高TG血症、低HDL－C血症、高LDL－C血症均是乳腺癌远处转移的危险因素。结论高脂血症与乳腺癌远处转移密切相关。有效监测患者血脂有助于预测乳腺癌远处转移。
목적：탐토혈지대유선암원처전이적예측개치。방법선취해원2011년12월지2013년12월진치적유선암환자115례위관찰조，근거암세포전이정황분위량조，78례환자미발생암세포원처전이위A조，37례환자발생암세포원처전이위B 조。선취본원동기건강체검인원115례위대조조。균행혈지상검측。분석혈지여유선암원처전이적관계。결과관찰조환자총담고순（TC）、감유삼지（TG）、저밀도지단백담고순（LDL－C）균명현고우대조조，관찰조환자고밀도지단백담고순（HDL－C）명현저우대조조，B조환자 TC、TG、LDL－C 균명현고우원위조，전이조환자HDL－C명현저우A조（P＜0．05）。고TC혈증、고TG혈증、저HDL－C혈증、고LDL－C혈증균시유선암원처전이적위험인소。결론고지혈증여유선암원처전이밀절상관。유효감측환자혈지유조우예측유선암원처전이。
Objective To investigate predictive value of lipid phase in breast cancer metastasis .Methods 115 patients with breast cancer were selected as observation group .According to cancer cell metastasis ,78 patients without cancer cell metastasis were as A group ,37 patients with cancer cell metastasis as B group .115 health physical examination personnel were selected as control group .All people were tea-ted the levels of lipid .Relationship between breast cancer metastasis and each indexes of lipid was analyzed .Results The levels of total cho-lesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C) in observation group were significantly higher than those of con-trol group.The level of high density lipoprotein cholesterol (HDL-C) in observation group was significantly lower than that of control group . The levels of TC,TG,LDL-D in B group were significantly higher than those of A group ,the level of HDL-C in B group was significantly lower than that of A group(P<0.05).Hypercholesterolemia,hypertriglyceridemia,low HDL-C,high LDL-C were risk factors of breast cancer metas-tasis.Conclusions Hyperlipidemia is closely related to breast cancer metastasis .Effective monitoring of blood lipid is helpful to predict breast cancer metastasis .