中华实验和临床感染病杂志（电子版）
中華實驗和臨床感染病雜誌（電子版）
중화실험화림상감염병잡지（전자판）
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL INFECTIOUS DISEASES(ELECTRONIC VERSION)
2015年
4期
513-515
,共3页
多重耐药菌%感染因素%预防措施
多重耐藥菌%感染因素%預防措施
다중내약균%감염인소%예방조시
Multi-resistant bacteria%Infection factor%Prevention measure
目的：探讨多重耐药菌感染在医院的预防措施，以期指导控制医院多重耐药菌的感染。方法收集中国医科大学航空总医院呼吸科病房2013年10月至2014年9月多重耐药菌感染者共70例，进行常规痰培养、尿培养和血培养，应用VITEK-2鉴定系统进行微生物鉴定和药敏分析，采用WHONET 5.6软件对药敏结果进行分析。结果共分离多重耐药菌68株，居前3位菌株依次为鲍曼不动杆菌。铜绿假单胞菌和黏质沙雷菌，分别占42.6%（29/68）、39.7%（27/68）和8.8%（6/68）；革兰阳性菌对万古霉素有较高的抗菌性，耐药率为7.9%。革兰阴性菌对替加环素有较高的抗菌性，耐药率为1.7%。结论加强对多重耐药菌的监测，及时发现和确诊，根据药敏试验合理选用抗菌药物，严格执行手卫生规范，加强医护人员无菌操作观念，培训护工保洁对多重耐药菌的认知，加强环境消毒，避免感染的传播。
目的：探討多重耐藥菌感染在醫院的預防措施，以期指導控製醫院多重耐藥菌的感染。方法收集中國醫科大學航空總醫院呼吸科病房2013年10月至2014年9月多重耐藥菌感染者共70例，進行常規痰培養、尿培養和血培養，應用VITEK-2鑒定繫統進行微生物鑒定和藥敏分析，採用WHONET 5.6軟件對藥敏結果進行分析。結果共分離多重耐藥菌68株，居前3位菌株依次為鮑曼不動桿菌。銅綠假單胞菌和黏質沙雷菌，分彆佔42.6%（29/68）、39.7%（27/68）和8.8%（6/68）；革蘭暘性菌對萬古黴素有較高的抗菌性，耐藥率為7.9%。革蘭陰性菌對替加環素有較高的抗菌性，耐藥率為1.7%。結論加彊對多重耐藥菌的鑑測，及時髮現和確診，根據藥敏試驗閤理選用抗菌藥物，嚴格執行手衛生規範，加彊醫護人員無菌操作觀唸，培訓護工保潔對多重耐藥菌的認知，加彊環境消毒，避免感染的傳播。
목적：탐토다중내약균감염재의원적예방조시，이기지도공제의원다중내약균적감염。방법수집중국의과대학항공총의원호흡과병방2013년10월지2014년9월다중내약균감염자공70례，진행상규담배양、뇨배양화혈배양，응용VITEK-2감정계통진행미생물감정화약민분석，채용WHONET 5.6연건대약민결과진행분석。결과공분리다중내약균68주，거전3위균주의차위포만불동간균。동록가단포균화점질사뢰균，분별점42.6%（29/68）、39.7%（27/68）화8.8%（6/68）；혁란양성균대만고매소유교고적항균성，내약솔위7.9%。혁란음성균대체가배소유교고적항균성，내약솔위1.7%。결론가강대다중내약균적감측，급시발현화학진，근거약민시험합리선용항균약물，엄격집행수위생규범，가강의호인원무균조작관념，배훈호공보길대다중내약균적인지，가강배경소독，피면감염적전파。
Objective To explore the prevention measures for multiple resistant bacteria infections, and to prevent the multiple resistant bacteria infections. Methods Total of 70 patients with multiple resistant bacteria infections, who were treated in the Respiratory Department, Aviation General Hospital of China Medical University from October 2013 to September 2014, then the routine sputum culture, uncle culture and blood culture, the bacterial susceptibilities to majority of antimicrobial agents were determined by VITEK-2 compact, respectively. The results were analyzed with WHONET 5.6 software. Results Total of 68 strains of multiple resistant bacteric were isolated, among which the Acinetobacter baumannii, Pseudomonas aeruginosa and Serratia marcescens ranked the top three species, accounting for 42.6% (29/68), 39.7%(27/68) and 8.8%(6/68), respectively. The main Gram-positive bacteria remained high antibacterial activity against vancomycin, with the drug resistance rates of 7.9%, the main Gram-negative bacteria remained high antibacterial activity against tigecycline, with the drug resistance rates of 1.7%. Conclusions It is necessary to strengthen the detection of the multiple resistant bacteria, with the detection and diagnosis in a timely manner. It is necessary to choose sensitive antibiotics based on the result of drug susceptibility testing, strictly implement the hand hygiene, reinforce medical staff’s sterile operation concept. Train nursing workers and cleaning staff to better know multiple resistant bacteria. Intensify environment disinfection to avoid infections.
