CAJ | 학술논문

目的：探讨鼠神经生长因子（mouse nerve grouth factor，mNGF）辅助治疗突发性聋的疗效。方法回顾性分析2010年1月-2014年12月我院收治的50例采用鼠神经生长因子辅助治疗突发性聋患者的临床资料，并将同期除鼠神经生长因子外其他治疗相同病例135例作为对照，分析两组资料的构成情况，然后用SPSS软件回归分析鼠神经生长因子治疗突聋的疗效。结果治疗前后鼠神经生长因子的治疗有效（听阈提高15dB以上）率与对照组比较，差别有显著统计学意义（P<0.05），鼠神经生长因子组的治疗有效率与对照组相比有显著差别。结论鼠神经生长因子辅助治疗突发性聋能提高突发性耳聋的治疗疗效。
목적：탐토서신경생장인자（mouse nerve grouth factor，mNGF）보조치료돌발성롱적료효。방법회고성분석2010년1월-2014년12월아원수치적50례채용서신경생장인자보조치료돌발성롱환자적림상자료，병장동기제서신경생장인자외기타치료상동병례135례작위대조，분석량조자료적구성정황，연후용SPSS연건회귀분석서신경생장인자치료돌롱적료효。결과치료전후서신경생장인자적치료유효（은역제고15dB이상）솔여대조조비교，차별유현저통계학의의（P<0.05），서신경생장인자조적치료유효솔여대조조상비유현저차별。결론서신경생장인자보조치료돌발성롱능제고돌발성이롱적치료료효。
Objective To investigate the effect of nerve growth factor (mouse nerve grouth factor,mNGF) efficacy of adjuvant treatment of sudden deafness. Methods 50 cases with mouse nerve growth factor in adjuvant treatment of sudden deafness pa-tients clinical datas,between January 2010 and December 2014 in Jiangxi People's Hospital were analyzed retropectively and the same period in rat nerve growth factor other treatment was the same 135 cases as control ,composition analysis of two groups of data will be two groups of curative effect,and then by SPSS software regression analysis of mouse nerve growth factor in the treat-ment of sudden deafness. Results The treatment before and after the treatment of mouse nerve growth factor (threshold effectively improved more than 15dB) rate compared with the control group,there was significant difference (P<0.05),the treatment of mouse nerve growth factor group the effective rate of control group was significantly different compared with. Conclusion The rat nerve growth factor in adjuvant treatment of sudden deafness can improve the curative effect in the treatment of sudden deafness.