CAJ | 학술논문

目的：研究小儿肺炎继发性腹泻的相关因素及微生态制剂的预防作用。方法227例肺炎患儿随机分为预防组(113例)和非预防组(114例)，预防组患儿住院后给予抗菌药物与微生态制剂[枯草杆菌二连活菌颗粒(妈咪爱)]，非预防组在患儿腹泻出现后才加用妈咪爱。应用单因素分析， Logistic多因素回归分析危险因素和保护性因素。结果两组发生继发性腹泻例数比较差异有统计学意义(P<0.05)。Logistic多因素回归分析显示，年龄、住院时间、抗菌药物联合应用为小儿肺炎继发性腹泻的危险因素，微生态制剂预防性应用为保护性因素。结论年龄小、住院时间长以及抗菌药物联合应用会增加肺炎患儿继发性腹泻发生的危险性，微生态制剂预防性使用可以降低其发生率。
목적：연구소인폐염계발성복사적상관인소급미생태제제적예방작용。방법227례폐염환인수궤분위예방조(113례)화비예방조(114례)，예방조환인주원후급여항균약물여미생태제제[고초간균이련활균과립(마미애)]，비예방조재환인복사출현후재가용마미애。응용단인소분석， Logistic다인소회귀분석위험인소화보호성인소。결과량조발생계발성복사례수비교차이유통계학의의(P<0.05)。Logistic다인소회귀분석현시，년령、주원시간、항균약물연합응용위소인폐염계발성복사적위험인소，미생태제제예방성응용위보호성인소。결론년령소、주원시간장이급항균약물연합응용회증가폐염환인계발성복사발생적위험성，미생태제제예방성사용가이강저기발생솔。
Objective To research related factors and prevention effect by microecologics for pediatric pneumonia secondary diarrhea. Methods A total of 227 children with pneumonia were randomly divided into prevention group (113 cases) and non-prevention group (114 cases). The prevention group received antibacterial agents and microecologics after admission [bacillus subtilis double living bacterium particles (medilac-vita)], and the non-prevention group received medilac-vita after diarrhea. Risk factors and protective factors were analyzed by univariate and multivariate Logistic regression analysis. Results The difference of secondary diarrhea cases between the two groups had statistical significance (P<0.05). Multivariate Logistic regression analysis showed that age, hospital stay, and combination of antibacterial agents were the risk factors of pediatric pneumonia secondary diarrhea. Preventive application of microecologics provided the protective factor. Conclusion Young age, long hospital stay, and combination of antibacterial agents will increase the risk in occurrence of secondary diarrhea in pneumonia children. Prevention application of microecologics can reduce its incidence.