CAJ | 학술논문

目的：探讨百草枯中毒患者肺部CT密度变化与预后的关系。方法收集2012年5月—2014年4月在广西医科大学第一附属医院确诊为百草枯中毒的患者19例，存活7例（存活组），死亡12例（死亡组）。选择患者肺部CT不同病变区域横断位图片各2张，肺部CT采用image-pro plus 6.0软件测量各层肺部CT密度，比较存活组、死亡组患者左、右侧病变轻、重层肺部CT密度的大小。结果存活组患者左侧肺部CT密度30.5～83.7，右侧肺部CT密度26.1～79.1；死亡组患者左侧肺部CT密度38.5～184.8，右侧肺部CT密度35.7～183.9。存活组患者左、右侧病变轻层与病变重层肺部CT密度比较，差异无统计学意义（ P＞0.05）；死亡组患者左、右侧病变重层肺部CT密度较病变轻层升高（P＜0.05）。存活组与死亡组患者左、右侧病变轻层肺部CT密度比较，差异无统计学意义（P＞0.05）；死亡组患者左、右侧病变重层肺部CT密度较存活组升高（ P＜0.05）。结论影像学检查在百草枯中毒导致肺损伤的治疗过程中有重要评估作用，可通过测试肺部CT密度了解病情变化、指导诊疗和评估预后。
목적：탐토백초고중독환자폐부CT밀도변화여예후적관계。방법수집2012년5월—2014년4월재엄서의과대학제일부속의원학진위백초고중독적환자19례，존활7례（존활조），사망12례（사망조）。선택환자폐부CT불동병변구역횡단위도편각2장，폐부CT채용image-pro plus 6.0연건측량각층폐부CT밀도，비교존활조、사망조환자좌、우측병변경、중층폐부CT밀도적대소。결과존활조환자좌측폐부CT밀도30.5～83.7，우측폐부CT밀도26.1～79.1；사망조환자좌측폐부CT밀도38.5～184.8，우측폐부CT밀도35.7～183.9。존활조환자좌、우측병변경층여병변중층폐부CT밀도비교，차이무통계학의의（ P＞0.05）；사망조환자좌、우측병변중층폐부CT밀도교병변경층승고（P＜0.05）。존활조여사망조환자좌、우측병변경층폐부CT밀도비교，차이무통계학의의（P＞0.05）；사망조환자좌、우측병변중층폐부CT밀도교존활조승고（ P＜0.05）。결론영상학검사재백초고중독도치폐손상적치료과정중유중요평고작용，가통과측시폐부CT밀도료해병정변화、지도진료화평고예후。
Objective To investigate the relationship between the changes of lung CT density of patients with paraquat poisoning and prognosis.Methods 19 patients who were diagnosed with paraquat poisoning in the First Affiliated Hospital of Guangxi Medical University from May 2012 to April 2014.Among them, 7 patients survived ( survival group) and 12 patients died ( death group) .On both sides of lung, two cross-sectional lung CT images of a high-level lesion area and two cross-sectional lung CT images of a low-level lesion area were selected.Image-pro plus 6.0 was used in lung CT to determine the density of each layer.Comparison was made between survival group and death group in the density of the layer with high-level or low-level lesion on the right side or the left side.Results In the survival group, the lung CT density range was 30.5-83.7 on the left side and 26.1-79.1 on the right side; in the death group, the lung CT density range was 38.5-184.8 on the left side and 35.7-183.9 on the right side.The patients in the survival group were not significantly different ( P>0.05 ) in lung CT density between the layer with high -level lesion and the layer with low -level lesion on the left side or the right side; the patients in the death group had higher (P<0.05) lung CT density in the layer with high-level lesion than in the layer with low-level lesion on the left side or the right side.The survival group and the death group were not significantly different ( P>0.05) in the lung CT density of the layer with low-level lesion on the left side or the right side; the death group had higher ( P<0.05 ) lung CT density in the layer with high-level lesion on the left side or the right side than the survival group.Conclusion Imaging examination plays an important role in the treatment of lung injury caused by paraquat poisioning.The test of lung CT density could help monitor the changes of illness condition and provide guidance for the diagnosis, treatment and prognosis.