中国全科医学
中國全科醫學
중국전과의학
CHINESE GENERAL PRACTICE
2015年
21期
2594-2598
,共5页
脓毒症%肾上腺功能不全%糖皮质激素类
膿毒癥%腎上腺功能不全%糖皮質激素類
농독증%신상선공능불전%당피질격소류
Sepsis%Adrenal insufficiency%Glucocorticoids
近年来脓毒症患者常见的并发症是肾上腺功能不全(AI),同时也可能出现相对肾上腺功能不全( RAI),导致其体内血浆皮质醇水平降低,造成高病死率。但近年的研究中,关于脓毒症合并AI/RAI尚缺乏深层的认识,而且目前尚无统一的诊断标准。本文介绍了脓毒症合并AI/RAI的流行病学、发病机制、诊断标准及治疗干预,表明糖皮质激素可以通过升高脓毒症合并AI/RAI患者的血浆皮质醇水平,改善预后。
近年來膿毒癥患者常見的併髮癥是腎上腺功能不全(AI),同時也可能齣現相對腎上腺功能不全( RAI),導緻其體內血漿皮質醇水平降低,造成高病死率。但近年的研究中,關于膿毒癥閤併AI/RAI尚缺乏深層的認識,而且目前尚無統一的診斷標準。本文介紹瞭膿毒癥閤併AI/RAI的流行病學、髮病機製、診斷標準及治療榦預,錶明糖皮質激素可以通過升高膿毒癥閤併AI/RAI患者的血漿皮質醇水平,改善預後。
근년래농독증환자상견적병발증시신상선공능불전(AI),동시야가능출현상대신상선공능불전( RAI),도치기체내혈장피질순수평강저,조성고병사솔。단근년적연구중,관우농독증합병AI/RAI상결핍심층적인식,이차목전상무통일적진단표준。본문개소료농독증합병AI/RAI적류행병학、발병궤제、진단표준급치료간예,표명당피질격소가이통과승고농독증합병AI/RAI환자적혈장피질순수평,개선예후。
Adrenal insufficiency is a common complication in patients with sepsis in recent years of Beijing PLA, andrelative adrenal insufficiency may also occur.It may lead to the reduction of plasma cortisol level and high mortality in patients.But in the researches of recent years, there is a lack of deeper understanding about adrenal insufficiency, and there is no unified diagnostic criterion.This paper introduced the epidemiology, pathogenesis, main diagnostic criteria and treatment intervention of sepsis complicated with adrenal insufficiency.It was indicated that glucocorticoids could improve prognosis by raising the plasma cortisol level in patients with sepsis complicated with AI/RAI.