中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
24期
61-64
,共4页
范子凡%利定良%吴其婷%冯荣添%戴伯宏%敖艳云%林露
範子凡%利定良%吳其婷%馮榮添%戴伯宏%敖豔雲%林露
범자범%리정량%오기정%풍영첨%대백굉%오염운%림로
麻疹%免疫率%阳性率%保护率%几何平均滴度
痳疹%免疫率%暘性率%保護率%幾何平均滴度
마진%면역솔%양성솔%보호솔%궤하평균적도
Measles%Vaccine rate%Positive rate%Protection rate%Geometric mean titer
目的：了解阳江市健康人群麻疹疫苗免疫状况和IgG抗体水平，为控制和消除麻疹提供参考依据。方法：采取分层随机抽样的方法，在辖区内共抽取20个乡镇，每个乡镇调查≥48个健康人，用酶联免疫吸附试验检测麻疹IgG抗体。结果：麻疹疫苗免疫率为87.11%，抗体阳性率为80.28％，抗体保护率为39.72％，抗体几何平均滴度（GMT）为1∶570.72。在麻疹抗体阳性率、保护率、GMT中，不同年龄组和不同地区的差异均有统计学意义。不同性别阳性率和保护率的差异均有统计学意义，GMT差异无统计学意义。有免疫史的人群中，阳性率差异有统计学意义，保护率和GMT的差异均无统计学意义。无免疫史与接种3剂次以上人群的麻疹抗体阳性率差异无统计学意义，两类人群的保护率和GMT各自的差异有统计学意义。结论：阳江市健康人群的麻疹抗体未能形成有效的免疫屏障，应加强复种，倡导接种含麻疹成分联合疫苗。
目的：瞭解暘江市健康人群痳疹疫苗免疫狀況和IgG抗體水平，為控製和消除痳疹提供參攷依據。方法：採取分層隨機抽樣的方法，在轄區內共抽取20箇鄉鎮，每箇鄉鎮調查≥48箇健康人，用酶聯免疫吸附試驗檢測痳疹IgG抗體。結果：痳疹疫苗免疫率為87.11%，抗體暘性率為80.28％，抗體保護率為39.72％，抗體幾何平均滴度（GMT）為1∶570.72。在痳疹抗體暘性率、保護率、GMT中，不同年齡組和不同地區的差異均有統計學意義。不同性彆暘性率和保護率的差異均有統計學意義，GMT差異無統計學意義。有免疫史的人群中，暘性率差異有統計學意義，保護率和GMT的差異均無統計學意義。無免疫史與接種3劑次以上人群的痳疹抗體暘性率差異無統計學意義，兩類人群的保護率和GMT各自的差異有統計學意義。結論：暘江市健康人群的痳疹抗體未能形成有效的免疫屏障，應加彊複種，倡導接種含痳疹成分聯閤疫苗。
목적：료해양강시건강인군마진역묘면역상황화IgG항체수평，위공제화소제마진제공삼고의거。방법：채취분층수궤추양적방법，재할구내공추취20개향진，매개향진조사≥48개건강인，용매련면역흡부시험검측마진IgG항체。결과：마진역묘면역솔위87.11%，항체양성솔위80.28％，항체보호솔위39.72％，항체궤하평균적도（GMT）위1∶570.72。재마진항체양성솔、보호솔、GMT중，불동년령조화불동지구적차이균유통계학의의。불동성별양성솔화보호솔적차이균유통계학의의，GMT차이무통계학의의。유면역사적인군중，양성솔차이유통계학의의，보호솔화GMT적차이균무통계학의의。무면역사여접충3제차이상인군적마진항체양성솔차이무통계학의의，량류인군적보호솔화GMT각자적차이유통계학의의。결론：양강시건강인군적마진항체미능형성유효적면역병장，응가강복충，창도접충함마진성분연합역묘。
Objective:To understand the immune status of measles vaccine and IgG antibody level in healthy population in Yangjiang city and to provide reference for controlling and eliminating measles.Method:More than or equal to 48 healthy people were investigated in each township by stratified random sampling method in a total 20 townships,measles IgG antibody were detected by using enzyme linked immunosorbent test.Result:The measles vaccine immunization rate was 87.11%,the positive rate of antibody was 80.28%,the antibody protection rate was 39.72%,and the geometric mean titer(GMT)of antibody was 1∶570.72. In different age groups and different regions,the positive rate of measles antibody,protective rate and GMT were statistically significant. There were significant differences in the positive rate and the protection rate among different gender groups,and the difference of GMT was not statistically significant. There was significant difference in the positive rate among the population with immune history,but the difference of protection rate and GMT was not statistically significant.There was no significant difference in the positive rate of measles antibody in the population with no immunity history and the 3 doses vaccination.Conclusion:The healthy population in Yangjiang city of measles antibodies failed to form an effective immune barrier and should be strengthen the multiple cropping,advocating vaccination with measles containing vaccine.
