心血管康复医学杂志
心血管康複醫學雜誌
심혈관강복의학잡지
JOURNAL OF CARDIOVASCULAR REHABILITATION MEDICINE
2015年
4期
394-397
,共4页
高血压%高血压性视网膜病变%血流动力学
高血壓%高血壓性視網膜病變%血流動力學
고혈압%고혈압성시망막병변%혈류동역학
Hypertension%Hypertensive retinopathy%Hemodynamics
目的：探讨高血压伴视网膜病变患者的脑血流动力学变化。方法：选择77例高血压伴视网膜病变患者归入研究组，同一时期入院体检正常的70例对象为正常对照组。比对两组患者大脑中动脉（MCA）、大脑前动脉（ACA）各指标的变化，记录眼动脉（OA）、视网膜中央动脉（CRA）血流动力学的变化。结果：与正常对照组比较：①研究组患者 MCA、ACA 的平均血流速度[（64.28±13.29）cm／s、（20.12±7.21）cm／s 比（129.18±20.14）cm／s、（89.35±10.98）cm／s]显著升高（P 均＜0.01）；②研究组各级别视网膜病变的患者 OA 及 CRA的收缩期峰值流速（PSV）和舒张末期血流速度（EDV）值均明显降低（P 均＜0.05），RI 指数明显升高（P ＜0.05）；③研究组患者的基底动脉平均血流速度[（21.62±7.36）ml／s 比（13.47±5.13）ml／s]、最大血流速度和最小血流速度等均明显降低（P 均＜0.01），脉搏波波速、外周阻力、临界压、血管特性阻抗[（17.35±5.36）kPa ·s／m 比（31.68±6.47）kPa·s－1·m－1]、动态阻力[（30.59±6.98）kPa·s－1·m－1比（64.48±12.38）kPa· s－1·m－1]等指标均显著升高（P 均＜0.01）。结论：高血压伴视网膜病变患者的脑供血指标随着血压的升高而降低，视网膜中央动脉血流变化可作为该疾病的病程发展判断依据，需引起患者及医师的高度注意。
目的：探討高血壓伴視網膜病變患者的腦血流動力學變化。方法：選擇77例高血壓伴視網膜病變患者歸入研究組，同一時期入院體檢正常的70例對象為正常對照組。比對兩組患者大腦中動脈（MCA）、大腦前動脈（ACA）各指標的變化，記錄眼動脈（OA）、視網膜中央動脈（CRA）血流動力學的變化。結果：與正常對照組比較：①研究組患者 MCA、ACA 的平均血流速度[（64.28±13.29）cm／s、（20.12±7.21）cm／s 比（129.18±20.14）cm／s、（89.35±10.98）cm／s]顯著升高（P 均＜0.01）；②研究組各級彆視網膜病變的患者 OA 及 CRA的收縮期峰值流速（PSV）和舒張末期血流速度（EDV）值均明顯降低（P 均＜0.05），RI 指數明顯升高（P ＜0.05）；③研究組患者的基底動脈平均血流速度[（21.62±7.36）ml／s 比（13.47±5.13）ml／s]、最大血流速度和最小血流速度等均明顯降低（P 均＜0.01），脈搏波波速、外週阻力、臨界壓、血管特性阻抗[（17.35±5.36）kPa ·s／m 比（31.68±6.47）kPa·s－1·m－1]、動態阻力[（30.59±6.98）kPa·s－1·m－1比（64.48±12.38）kPa· s－1·m－1]等指標均顯著升高（P 均＜0.01）。結論：高血壓伴視網膜病變患者的腦供血指標隨著血壓的升高而降低，視網膜中央動脈血流變化可作為該疾病的病程髮展判斷依據，需引起患者及醫師的高度註意。
목적：탐토고혈압반시망막병변환자적뇌혈류동역학변화。방법：선택77례고혈압반시망막병변환자귀입연구조，동일시기입원체검정상적70례대상위정상대조조。비대량조환자대뇌중동맥（MCA）、대뇌전동맥（ACA）각지표적변화，기록안동맥（OA）、시망막중앙동맥（CRA）혈류동역학적변화。결과：여정상대조조비교：①연구조환자 MCA、ACA 적평균혈류속도[（64.28±13.29）cm／s、（20.12±7.21）cm／s 비（129.18±20.14）cm／s、（89.35±10.98）cm／s]현저승고（P 균＜0.01）；②연구조각급별시망막병변적환자 OA 급 CRA적수축기봉치류속（PSV）화서장말기혈류속도（EDV）치균명현강저（P 균＜0.05），RI 지수명현승고（P ＜0.05）；③연구조환자적기저동맥평균혈류속도[（21.62±7.36）ml／s 비（13.47±5.13）ml／s]、최대혈류속도화최소혈류속도등균명현강저（P 균＜0.01），맥박파파속、외주조력、림계압、혈관특성조항[（17.35±5.36）kPa ·s／m 비（31.68±6.47）kPa·s－1·m－1]、동태조력[（30.59±6.98）kPa·s－1·m－1비（64.48±12.38）kPa· s－1·m－1]등지표균현저승고（P 균＜0.01）。결론：고혈압반시망막병변환자적뇌공혈지표수착혈압적승고이강저，시망막중앙동맥혈류변화가작위해질병적병정발전판단의거，수인기환자급의사적고도주의。
Objective:To explore the cerebral hemodynamic changes of patients with hypertension complicated reti-nopathy.Methods:A total of 77 patients with hypertension complicated retinopathy were enrolled as study group, another 70 patients,who received physical examination during the same period and its results were normal,were treated as normal control group.Index changes of middle cerebral artery (MCA)and anterior cerebral artery (ACA)were compared between two groups,and hemodynamic difference of ophthalmic artery (OA)and central retinal artery (CRA)were recorded.Results:Compared with normal control group:① Mean velocity of MCA and ACA [(64.28±13.29)cm/s,(20.12±7.21)cm/s vs.(129.18±20.14)cm/s,(89.35±10.98)cm/s]signifi-cantly rose in study group ,P <0.01 all;②There were significant reductions in peak systolic velocity (PSV)and end-diastolic velocity (EDV)of OA and CRA,P <0.05 all,and resistance index significantly rose in all classes of study group (P <0.05 all);③There were significant reductions in mean blood flow velocity [(21.62±7.36)ml/s vs.(13.47±5.13)ml/s],maximum blood flow velocity and minimum blood flow velocity ,and significant rise in pulse wave velocity,peripheral resistance,critical pressure,vascular characteristic impedance [(17.35±5.36)kPa ·s-1 ·m-1 vs.(31.68±6.47)kPa· s-1 · m-1 ],and dynamic resistance [(30.59 ± 6.98)kPa· s-1 · m-1 vs. (64.48±12.38)kPa·s-1 ·m-1 ],in basilar artery in study group,P <0.01 all.Conclusion:In patients with hy-pertension complicated retinopathy,cerebral blood supply indexes reduce along with blood pressure rises,CRA blood flow changes can be regarded as a judging basis for disease course development,which deserves highly atten-tion for patients and physicians.
