CAJ | 학술논문

目的：：观察妊娠期糖尿病(GDM)患者血浆 D-二聚体和国际标准化比值(INR)水平变化。方法：随机选取孕34周以上 GDM 患者50例(GDM 组),孕34周以上正常妇女52例(对照组),分别用免疫比浊法和凝固法检测两组孕妇血浆 D-二聚体浓度和 INR[通过凝血酶原时间(PT)计算],对比分析组间差异。结果：GDM 组患者D-二聚体浓度显著高于对照组(2.54±1.83 vs 1.83±0.95,P <0.05)；GDM 组 INR 虽低于对照组,但差异无统计学意义(0.99±0.20 vs 1.02±0.37,P >0.05)。结论：GDM 患者的血液凝固性和纤溶代偿功能均高于正常孕妇,需防范其血栓并发症及产后出血。
목적：：관찰임신기당뇨병(GDM)환자혈장 D-이취체화국제표준화비치(INR)수평변화。방법：수궤선취잉34주이상 GDM 환자50례(GDM 조),잉34주이상정상부녀52례(대조조),분별용면역비탁법화응고법검측량조잉부혈장 D-이취체농도화 INR[통과응혈매원시간(PT)계산],대비분석조간차이。결과：GDM 조환자D-이취체농도현저고우대조조(2.54±1.83 vs 1.83±0.95,P <0.05)；GDM 조 INR 수저우대조조,단차이무통계학의의(0.99±0.20 vs 1.02±0.37,P >0.05)。결론：GDM 환자적혈액응고성화섬용대상공능균고우정상잉부,수방범기혈전병발증급산후출혈。
Objective:To observe the changes of plasma D-dimer and international normalized ratio (INR)lev-el in gestational diabetes mellitus (GDM)patients.Method:50 cases of gestational diabetes over 34 gestational weeks were randomly selected into GDM group;52 normal pregnant women over 34 gestational weeks as the control group,both groups were tested for maternal plasma D-dimer and INR levels and were comparatived for analysis. Results:GDM group D-dimer was higher than the control group(2.54 ± 1.83 vs 1.83 ± 0.95,P < 0.05 );GDM group INR lower than the control group,but the difference was not statistically significant (0.99±0.20 vs 1.02± 0.37,P >0.05).Conclusion:GDM patients blood coagulation and fibrinolysis compensatory function were higher than normal pregnant women,and therefore need to prevent thrombotic complications and postpartum hemorrhage.