中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
23期
74-76,79
,共4页
张映辉%梁娇%沈柏儒%林思瑶%杨成刚%甄曼华
張映輝%樑嬌%瀋柏儒%林思瑤%楊成剛%甄曼華
장영휘%량교%침백유%림사요%양성강%견만화
过敏家族史%母亲血IgE%脐血IgE%婴儿过敏性疾病
過敏傢族史%母親血IgE%臍血IgE%嬰兒過敏性疾病
과민가족사%모친혈IgE%제혈IgE%영인과민성질병
Family history of allergy%Maternal blood IgE%Cord blood IgE%Infant allergic disease
目的：研究脐血IgE及母血IgE与婴儿过敏性疾病的关系，探讨母亲过敏史与婴儿过敏性疾病的相关性。方法选取2011年3月~2012年2月在佛山市禅城区中心医院产检的孕妇共40例，对孕妇进行过敏性疾病问卷调查，孕期行母血IgE、分娩后行脐血IgE检测。对出生后的婴儿进行为期6个月的随访，观察婴儿有无出现过敏性疾病。结果脐血IgE与母血IgE水平差异有统计学意义(P<0.05)。母亲有过敏史及无过敏史组的母血IgE水平差异无统计学意义(P跃0.05)，脐血IgE水平差异有统计学意义(P<0.05)，婴儿过敏性疾病发生率差异无统计学意义(P>0.05)。新生儿脐血IgE水平正常组(IgE<350 U/L)与升高组(IgE≥350 U/L)的过敏性疾病发生率差异有统计学意义(P<0.05)。结论母亲有过敏史更易提高胎儿的过敏风险，孕期监测母血IgE及脐血IgE对预测新生儿过敏性疾病有很大的临床价值，脐血IgE对于新生儿过敏性疾病的预测价值高于母血IgE。
目的：研究臍血IgE及母血IgE與嬰兒過敏性疾病的關繫，探討母親過敏史與嬰兒過敏性疾病的相關性。方法選取2011年3月~2012年2月在彿山市禪城區中心醫院產檢的孕婦共40例，對孕婦進行過敏性疾病問捲調查，孕期行母血IgE、分娩後行臍血IgE檢測。對齣生後的嬰兒進行為期6箇月的隨訪，觀察嬰兒有無齣現過敏性疾病。結果臍血IgE與母血IgE水平差異有統計學意義(P<0.05)。母親有過敏史及無過敏史組的母血IgE水平差異無統計學意義(P躍0.05)，臍血IgE水平差異有統計學意義(P<0.05)，嬰兒過敏性疾病髮生率差異無統計學意義(P>0.05)。新生兒臍血IgE水平正常組(IgE<350 U/L)與升高組(IgE≥350 U/L)的過敏性疾病髮生率差異有統計學意義(P<0.05)。結論母親有過敏史更易提高胎兒的過敏風險，孕期鑑測母血IgE及臍血IgE對預測新生兒過敏性疾病有很大的臨床價值，臍血IgE對于新生兒過敏性疾病的預測價值高于母血IgE。
목적：연구제혈IgE급모혈IgE여영인과민성질병적관계，탐토모친과민사여영인과민성질병적상관성。방법선취2011년3월~2012년2월재불산시선성구중심의원산검적잉부공40례，대잉부진행과민성질병문권조사，잉기행모혈IgE、분면후행제혈IgE검측。대출생후적영인진행위기6개월적수방，관찰영인유무출현과민성질병。결과제혈IgE여모혈IgE수평차이유통계학의의(P<0.05)。모친유과민사급무과민사조적모혈IgE수평차이무통계학의의(P약0.05)，제혈IgE수평차이유통계학의의(P<0.05)，영인과민성질병발생솔차이무통계학의의(P>0.05)。신생인제혈IgE수평정상조(IgE<350 U/L)여승고조(IgE≥350 U/L)적과민성질병발생솔차이유통계학의의(P<0.05)。결론모친유과민사경역제고태인적과민풍험，잉기감측모혈IgE급제혈IgE대예측신생인과민성질병유흔대적림상개치，제혈IgE대우신생인과민성질병적예측개치고우모혈IgE。
Objective To investigate the relationship between cord blood IgE,maternal blood IgE and infant allergic dis-ease to discuss the correlation between mother’s allergic history and infant allergic disease. Methods 40 pregnant women given antenatal care in Chancheng District Central Hospital of Foshan City from March 2011 to Februar 2012 were selected,and questionnaire survey of allergic disease was conducted for pregnant women respectively.Detection of maternal blood IgE and cord blood IgE was conducted during pregnancy and after delivery.Infants after birth were fol-lowed-up for 6 months,whether there was an allergic disease in infant was observed. Results There was a statistical difference of cord blood IgE and maternal blood IgE level (P<0.05).There was no statistical difference of maternal blood IgE level (P>0.05),and there was a statistical difference of cord blood IgE level (P<0.05),and there was no statistical difference of the incidence rate of infant allergic disease (P>0.05) between mother having history of allergy group and mother having no history of allergy group.There was a statistical difference of the incidence rate of allergic disease be-tween neonatal normal cord blood IgE level group (IgE<350 U/L) and neonatal elevated cord blood IgE level group (IgE≥350 U/L) (P<0.05). Conclusion Mother with a history of allergy is more likely to raise allergy risk of fetus,mater-nal blood IgE and cord blood IgE monitored during has a great clinical value,and predictive value of cord blood IgE is higher than maternal blood IgE for neonatal allergic disease.
