CAJ | 학술논문

目的：：回顾性分析 D-二聚体和降钙素原水平在老年脓毒症患者中的变化。方法：将172例老年脓毒症患者按预后分为生存组(n=115)和死亡组(n=57)；采用免疫比浊法和电化学发光法分别检测两组患者入院时血浆 D-二聚体和降钙素原水平,比较血浆 D-二聚体、降钙素原水平和急性生理与慢性健康状况评分(APACHEⅡ评分)的组间差异及其相关性。结果：生存组血浆 D-二聚体和降钙素原水平和 APACHEⅡ评分均低于死亡组(P<0.01)；老年脓毒症患者血浆 D-二聚体和降钙素原水平与 APACHEⅡ评分存在明显正相关性(r 分别为0.352、0.234,P <0.05)。结论：不同预后的老年脓毒症患者血浆 D-二聚体和降钙素原水平存在差异,监测这两个生物学指标对老年脓毒症患者的预后具有一定的参考价值。
목적：：회고성분석 D-이취체화강개소원수평재노년농독증환자중적변화。방법：장172례노년농독증환자안예후분위생존조(n=115)화사망조(n=57)；채용면역비탁법화전화학발광법분별검측량조환자입원시혈장 D-이취체화강개소원수평,비교혈장 D-이취체、강개소원수평화급성생리여만성건강상황평분(APACHEⅡ평분)적조간차이급기상관성。결과：생존조혈장 D-이취체화강개소원수평화 APACHEⅡ평분균저우사망조(P<0.01)；노년농독증환자혈장 D-이취체화강개소원수평여 APACHEⅡ평분존재명현정상관성(r 분별위0.352、0.234,P <0.05)。결론：불동예후적노년농독증환자혈장 D-이취체화강개소원수평존재차이,감측저량개생물학지표대노년농독증환자적예후구유일정적삼고개치。
Objective:To analysis the changes of D-dimer,procalcitonin levels in elderly patients with sepsis. Method:1 72 cases of elderly patients with sepsis were divided into survival group (n=1 1 5)and death group (n=57).When patients admitted to hospital,immune turbidimetric method and electrochemical luminescence method were used respectively to detect the plasma D-dimer and procalcitonin levels.The plasma D-dimer,procalcitonin lev-els and acute physiology and chronic health evaluation (APACHE Ⅱ score)differences between groups and their correlation were analyzed.Results:Survival group of plasma D-dimer and procalcitonin levels and APACHE Ⅱscores were lower than the death group with statistical significance (P <0.01 ).Plasma D-dimer and procalcitonin levels and APACHE Ⅱ scores were significantly positive correlations (r = 0.352,0.234,P < 0.05 ).Conclusion:There were differences in plasma of D-dimer and procalcitonin levels of in the elderly sepsis patients with different prognosis.The two biological indicators had certain reference value for the prognosis of elderly patients with sepsis.