CAJ | 학술논문

目的：分析并探讨前列腺穿刺活检中血清高敏 C 反应蛋白（hs －CRP）测定的临床意义。方法：选取2012年2月至2015年2月期间在我院接受前列腺穿刺活检患者275例。病理诊断为良性前列腺增生（BPH）患者178例，病理诊断为 PCa 患者97例。检测患者 hs －CRP 含量及其他各项指标含量。结果：BPH 患者 hs －CRP 为（1.24±0.37）mg／L，PCa 患者 hs －CRP 为（3.21±0.89）mg／L。PCa 患者 hs －CRP明显高于 BPH 患者。经统计学检验，差异具有统计学意义（P ＜0.05）。hs －CRP 升高（大于3mg／L）患者93例，其中 PCa52例，穿刺阳性率为55.91％。hs －CRP 正常（小于等于3mg／L）患者182例，其中 PCa45例，穿刺阳性率为24.73％。hs －CRP 升高穿刺阳性率明显升高。经统计学检验，差异具有统计学意义（P ＜0.05）。年龄、tPSA、TPV 和 hs －CRP 是影响前列腺穿刺阳性率的独立因素（P ＜0.05）。结论：血清高敏 C 反应蛋白是影响前列腺穿刺阳性率的独立因素，当血清高敏 C 反应蛋白升高时，穿刺阳性率明显升高，对于疾病诊断具有提示作用。
목적：분석병탐토전렬선천자활검중혈청고민 C 반응단백（hs －CRP）측정적림상의의。방법：선취2012년2월지2015년2월기간재아원접수전렬선천자활검환자275례。병리진단위량성전렬선증생（BPH）환자178례，병리진단위 PCa 환자97례。검측환자 hs －CRP 함량급기타각항지표함량。결과：BPH 환자 hs －CRP 위（1.24±0.37）mg／L，PCa 환자 hs －CRP 위（3.21±0.89）mg／L。PCa 환자 hs －CRP명현고우 BPH 환자。경통계학검험，차이구유통계학의의（P ＜0.05）。hs －CRP 승고（대우3mg／L）환자93례，기중 PCa52례，천자양성솔위55.91％。hs －CRP 정상（소우등우3mg／L）환자182례，기중 PCa45례，천자양성솔위24.73％。hs －CRP 승고천자양성솔명현승고。경통계학검험，차이구유통계학의의（P ＜0.05）。년령、tPSA、TPV 화 hs －CRP 시영향전렬선천자양성솔적독립인소（P ＜0.05）。결론：혈청고민 C 반응단백시영향전렬선천자양성솔적독립인소，당혈청고민 C 반응단백승고시，천자양성솔명현승고，대우질병진단구유제시작용。
Objectives:To analyze and discuss the clinical significance of prostate biopsy in patients with serum high -sensitivity C -reactive protein measurement.Methods:275 patients received prostate biopsy in our hospital from February 201 2 to February 201 5 were selected.There were 1 78 cases of benign prostatic hyperplasia (BPH)and 97 cases of PCa.Hs -CRP and other indexes content were measured.Results:Hs -CRP of BPH pa-tients and PCa patients was (1 .24 ±0.37)mg /L and (3.21 ±0.89)mg/L respectively,with statistically sig-nificant difference (P <0.05).There were 93 cases with increasing hs -CRP (greater than 3mg /L),of which there were 52 cases of PCa and the positive biopsy rate was 55.91 %.There were 1 82 cases with normal hs -CRP (less than or equal 3mg /L),of which there were 45 cases of PCa and the positive biopsy rate was 24.73%.The positive rate of increasing hs -CRP group was significantly higher,with statistically significant difference (P <0.05).Independent factors affecting prostate biopsy positive rate were age,tPSA,TPV and hs -CRP (P <0.05). Conclusion:The serum high -sensitivity C -reactive protein is an independent factor affecting the positive rate of prostate biopsy.As serum high -sensitivity C -reactive protein increases,the positive rate is significantly higher, which can be used as prompted action.