重庆医学
重慶醫學
중경의학
CHONGQING MEDICAL JOURNAL
2015年
24期
3374-3375,3380
,共3页
清蛋白尿%心血管系统%冠心病%冠状动脉疾病
清蛋白尿%心血管繫統%冠心病%冠狀動脈疾病
청단백뇨%심혈관계통%관심병%관상동맥질병
albuminuria%cardiovascular system%coronary disease%coronary artery disease
目的：探讨冠心病合并微量清蛋白尿(MAU)与心血管事件的相关性。方法连续选择该院冠心病患者共120例,根据尿清蛋白肌酐比值(UACR)分为观察组(30 mg/g< UACR<300 mg/g,n=80)和对照组(UACR≤30 mg/g,n=40),随访15个月后比较分析两组患者心血管事件与 MAU 水平的相关性。结果观察组的 MAU 水平显著高于对照组,差异有统计学意义(P <0.05)。观察组患者的心血管事件共发生163次,对照组57次,观察组的心血管事件发生率显著高于对照组,差异有统计学意义(t=3.717,P <0.05)。Spearman 相关分析可知,MAU 与心血管事件呈显著正相关(r =0.721,P <0.01)。影响因素有MAU(P =0.001)、C 反应蛋白(P =0.037)。结论MAU 浓度与冠心病患者心血管事件密切相关,可以预测心血管事件的发生。
目的：探討冠心病閤併微量清蛋白尿(MAU)與心血管事件的相關性。方法連續選擇該院冠心病患者共120例,根據尿清蛋白肌酐比值(UACR)分為觀察組(30 mg/g< UACR<300 mg/g,n=80)和對照組(UACR≤30 mg/g,n=40),隨訪15箇月後比較分析兩組患者心血管事件與 MAU 水平的相關性。結果觀察組的 MAU 水平顯著高于對照組,差異有統計學意義(P <0.05)。觀察組患者的心血管事件共髮生163次,對照組57次,觀察組的心血管事件髮生率顯著高于對照組,差異有統計學意義(t=3.717,P <0.05)。Spearman 相關分析可知,MAU 與心血管事件呈顯著正相關(r =0.721,P <0.01)。影響因素有MAU(P =0.001)、C 反應蛋白(P =0.037)。結論MAU 濃度與冠心病患者心血管事件密切相關,可以預測心血管事件的髮生。
목적：탐토관심병합병미량청단백뇨(MAU)여심혈관사건적상관성。방법련속선택해원관심병환자공120례,근거뇨청단백기항비치(UACR)분위관찰조(30 mg/g< UACR<300 mg/g,n=80)화대조조(UACR≤30 mg/g,n=40),수방15개월후비교분석량조환자심혈관사건여 MAU 수평적상관성。결과관찰조적 MAU 수평현저고우대조조,차이유통계학의의(P <0.05)。관찰조환자적심혈관사건공발생163차,대조조57차,관찰조적심혈관사건발생솔현저고우대조조,차이유통계학의의(t=3.717,P <0.05)。Spearman 상관분석가지,MAU 여심혈관사건정현저정상관(r =0.721,P <0.01)。영향인소유MAU(P =0.001)、C 반응단백(P =0.037)。결론MAU 농도여관심병환자심혈관사건밀절상관,가이예측심혈관사건적발생。
Objective To investigate the correlation between microalbuminuria and cardiovascular events in patients with coronary heart disease.Methods A total of 120 CHD patients were divided into experiment group (30 mg/g< UACR<300 mg/g, n=80)and control group(UACR≤30 mg/g,n=40)The relationship between MAU and cardiovascular events rate was compared after 1 5 months.Results Microalbuminuria level in experiment group was significantly higher than control group(P <0.05).The incidence of cardiovascular event in experiment group was significantly higher(t = 3.71 7,P <0.05 ).MAU and cardiovascular e-vents were positively related by Spearman′s analysis(r=0.721,P <0.01).The effective factors were MAU and CRP(MAU:P =0.001;CRP:P =0.037).Conclusion MAU concentration had a great impact on the incidence of cardiovascular event.The incidence of cardiovascular might be predicted by the MAU.
