CAJ | 학술논문

目的：探讨精神分裂症患者生活质量与药物治疗态度的相关性。方法连续入组151例在广州市脑科医院住院的符合《国际疾病分类（第10版）》（ICD -10）精神分裂症诊断标准的患者，分别采用健康状况量表（SF-36）、药物态度清单（DAI）、阳性和阴性症状量表（PANSS）评定其生活质量、药物治疗态度和临床症状。采用多重逐步回归分析生活质量的影响因素。结果治疗态度积极组57例，男性38例（66.7％），治疗态度消极组94例，男性40例（42.6％），积极组男性比例高于消极组；积极组 SF -36心理健康维度（MCS）评分（46.8±9.1）分，消极组（41.0±10.8）分，两组比较差异有统计学意义（P ＜0.05）；多重回归分析显示患者的药物治疗态度是生活质量的影响因素（B ＝2.025，β＝0.309，P ＜0.05）。结论精神分裂症患者的药物治疗态度越积极，生活质量越好。
목적：탐토정신분렬증환자생활질량여약물치료태도적상관성。방법련속입조151례재엄주시뇌과의원주원적부합《국제질병분류（제10판）》（ICD -10）정신분렬증진단표준적환자，분별채용건강상황량표（SF-36）、약물태도청단（DAI）、양성화음성증상량표（PANSS）평정기생활질량、약물치료태도화림상증상。채용다중축보회귀분석생활질량적영향인소。결과치료태도적겁조57례，남성38례（66.7％），치료태도소겁조94례，남성40례（42.6％），적겁조남성비례고우소겁조；적겁조 SF -36심리건강유도（MCS）평분（46.8±9.1）분，소겁조（41.0±10.8）분，량조비교차이유통계학의의（P ＜0.05）；다중회귀분석현시환자적약물치료태도시생활질량적영향인소（B ＝2.025，β＝0.309，P ＜0.05）。결론정신분렬증환자적약물치료태도월적겁，생활질량월호。
Objective To explore the correlation between quality of life and medication attitude among schizophrenic inpatients. Methods A total of 151 participants with schizophrenia were randomly recruited from Inpatient Department of Guangzhou Brain Hospi-tal. The Short Form 36 Health Survey Questionnaire(SF - 36),the Drug Attitude Inventory(DAI)and the Positive and Negative Syn-drome Scale(PANSS)were applied to assess quality of life,medication attitude and clinical symptoms respectively. According to DAI scores,participants were divided into positive medication attitude group and negative medication attitude group. Multiple stepwise regression analysis was applied to analyze the influencing factors of quality of life. Results 57 patients were in the positive medication attitude group with 38 males(66. 7% ),while 94 in the negative group with 40 males(42. 6% ),as a result,the percentage of males was higher in the positive group,the scores of Mental Component Summary(MCS)were(46. 8 ± 9. 1)and(41. 0 ± 10. 8)of the posi-tive and negative groups respectively,and the difference between the two groups was statistically significant(P < 0. 05). Multiple re-gression analysis showed that medication attitude is the influencing factor of quality of life in patients with schizophrenia(B = 2. 025,β= 0. 309,P < 0. 05). Conclusion Higher level of quality of life was correlated with better attitude toward medication.