CAJ | 학술논문

目的：探讨住院时间长短对精神分裂症患者出院时的自知力影响。方法在广州市脑科医院连续入组且符合《国际疾病分类（第10版）》（ICD -10）精神分裂症诊断标准的住院患者265例，采用阳性和阴性症状量表（PANSS）、自知力和治疗态度问卷（ITAQ）分别测评患者的精神症状和自知力。采用相关性分析及线性回归分析探索自知力和治疗态度的影响因素。结果本组患者住院天数中位数为61（35～97）天，出院时 ITAQ 评分（11.1±5.8）分。PANSS 各分量表、总评分及住院天数与 ITAQ 评分均有相关性（P ＜0.05）。线性回归分析显示PANSS 阳性症状、阴性症状和住院1年以上是自知力的危险因素（B ＝-0.403，-0.232，-2.979，P ＜0.05），住院天数对 ITAQ 的解释度仅为1.9％。结论患者出院时的自知力主要受精神症状影响，住院时间长短对自知力的影响不大，适度缩短精神分裂症患者住院天数对自知力恢复可能不会产生负面影响。
목적：탐토주원시간장단대정신분렬증환자출원시적자지력영향。방법재엄주시뇌과의원련속입조차부합《국제질병분류（제10판）》（ICD -10）정신분렬증진단표준적주원환자265례，채용양성화음성증상량표（PANSS）、자지력화치료태도문권（ITAQ）분별측평환자적정신증상화자지력。채용상관성분석급선성회귀분석탐색자지력화치료태도적영향인소。결과본조환자주원천수중위수위61（35～97）천，출원시 ITAQ 평분（11.1±5.8）분。PANSS 각분량표、총평분급주원천수여 ITAQ 평분균유상관성（P ＜0.05）。선성회귀분석현시PANSS 양성증상、음성증상화주원1년이상시자지력적위험인소（B ＝-0.403，-0.232，-2.979，P ＜0.05），주원천수대 ITAQ 적해석도부위1.9％。결론환자출원시적자지력주요수정신증상영향，주원시간장단대자지력적영향불대，괄도축단정신분렬증환자주원천수대자지력회복가능불회산생부면영향。
Objective To examine the impact of Length of stay(LOS)on insight in schizophrenic patients. Methods 265 in-patients who had been diagnosed with schizophrenia based on International Classification of Diseases,tenth edition(ICD - 10)diagnos-tic criteria were enrolled in Guangzhou Brian Hospital. Clinical symptoms and insight were assessed by Positive and Negative Syndrome Scale(PANSS)and Insight and Treatment Attitudes Questionnaire(ITAQ)respectively. Spearmen correlation analysis and linear regression analysis were used to examine predictors of insight. Results The median LOS was 61(35 ~ 97)days,and the average ITAQ score was(11. 1 ± 5. 8). The correlation analysis showed that positive correlations between PANSS score,LOS less than 3 months and ITAQ score,while negative correlations of LOS over 1 year with ITAQ. Linear regression analysis showed that negative symptoms,positive symptoms and LOS more than 1 year were risk factors for insight(B = - 0. 403,- 0. 232,- 2. 979,P < 0. 05),and LOS only accounted for 1. 9% of the variation in insight. Conclusion Insight was mainly affected by clinical symptoms not LOS in hospitalized patients with schizophrenia,and appropriately shortened LOS might not impair the improvement in insight.