临床肿瘤学杂志
臨床腫瘤學雜誌
림상종류학잡지
CHINESE CLINICAL ONCOLOGY
2015年
8期
760-764
,共5页
马晓霖(综述)%陈建平(审校)
馬曉霖(綜述)%陳建平(審校)
마효림(종술)%진건평(심교)
肝门部胆管癌%影像学技术%细胞学技术%肿瘤标志物
肝門部膽管癌%影像學技術%細胞學技術%腫瘤標誌物
간문부담관암%영상학기술%세포학기술%종류표지물
Hilar cholangiocarcinoma%Radiological technology%Cytological techniques%Tumor marker
肝门部胆管癌恶性程度高、发病隐匿，预后不良。根治性手术为首选治疗方法，但根治率低，因此早期诊断尤为重要。目前诊断主要依靠影像学技术如MRI、磁共振胰胆管造影（ MRCP ）等及内镜下逆行胰胆管造影术（ ERCP ）、超声内镜（ EUS）、组织学检查和肿瘤标志物。随着新发现的肿瘤标志物灵敏度、特异度的提高，探索新的肿瘤标志物为肝门部胆管癌早期诊断提供新思路。
肝門部膽管癌噁性程度高、髮病隱匿，預後不良。根治性手術為首選治療方法，但根治率低，因此早期診斷尤為重要。目前診斷主要依靠影像學技術如MRI、磁共振胰膽管造影（ MRCP ）等及內鏡下逆行胰膽管造影術（ ERCP ）、超聲內鏡（ EUS）、組織學檢查和腫瘤標誌物。隨著新髮現的腫瘤標誌物靈敏度、特異度的提高，探索新的腫瘤標誌物為肝門部膽管癌早期診斷提供新思路。
간문부담관암악성정도고、발병은닉，예후불량。근치성수술위수선치료방법，단근치솔저，인차조기진단우위중요。목전진단주요의고영상학기술여MRI、자공진이담관조영（ MRCP ）등급내경하역행이담관조영술（ ERCP ）、초성내경（ EUS）、조직학검사화종류표지물。수착신발현적종류표지물령민도、특이도적제고，탐색신적종류표지물위간문부담관암조기진단제공신사로。
The hilar cholangiocarcinoma with high malignant degree and insidious development, is associated with poor prog?nosis. Radical operation is the preferred treatment strategy but the cure rate is low. Thus it is very important to make early diagnosis. This paper summarizes the current diagnosis methods which relied mainly on imaging technology such as MRI and magnetic resonance cholangiopancreatography( MRCP ) , endoscopic retrograde cholangiopancreatography ( ERCP ) , endoscopic ultrasonography ( EUS ) , histological examination and tumor markers. With the improvement of sensitivity and specificity of the newly discovered tumor markers, it is the new method of early diagnosis of hilar cholangiocarcinoma to discover new tumor markers.
