CAJ | 학술논문

目的：探讨经阴道彩超检测子宫动脉、子宫内膜及内膜下血流对体外受精－胚胎移植（ in vitro fertilization－embryo transfer，IVF－ET）结局的影响。方法选取2010年6月至2012年6月安徽省妇幼保健院生殖中心行IVF－ET或卵胞浆内单精子注射（intracytoplasmic sperm injection，ICSI）治疗的165例患者的临床资料，根据妊娠结果分为妊娠组66例和未妊娠组99例。使用经阴道彩色多普勒超声成像技术监测注射人绒毛膜促性腺激素（ human chorionic gonadotropin， HCG）日子宫内膜厚度及类型，ET日子宫动脉的收缩期与舒张末期流速比值（systolic／diastolic ratio，S／D）、阻力指数（resisitance index，RI）、搏动指数（pulsatility index， PI）、子宫内膜及内膜下血流等指标，比较两组间的各项指标。结果两组子宫内膜厚度及子宫内膜类型比较差异无统计学意义（ P＞0.05）；妊娠组子宫内膜有血流所占比例[45.45％（30／66）]高于非妊娠组[25.25％（25／99）]（P＜0.05）；妊娠组子宫内膜下血流RI（0.30±0.05）低于非妊娠组（0.69±0.07）（P＜0.05）。结论经阴道彩超检测子宫内膜血流及子宫内膜下血流RI对IVF－ET结局有一定预测价值。
목적：탐토경음도채초검측자궁동맥、자궁내막급내막하혈류대체외수정－배태이식（ in vitro fertilization－embryo transfer，IVF－ET）결국적영향。방법선취2010년6월지2012년6월안휘성부유보건원생식중심행IVF－ET혹란포장내단정자주사（intracytoplasmic sperm injection，ICSI）치료적165례환자적림상자료，근거임신결과분위임신조66례화미임신조99례。사용경음도채색다보륵초성성상기술감측주사인융모막촉성선격소（ human chorionic gonadotropin， HCG）일자궁내막후도급류형，ET일자궁동맥적수축기여서장말기류속비치（systolic／diastolic ratio，S／D）、조력지수（resisitance index，RI）、박동지수（pulsatility index， PI）、자궁내막급내막하혈류등지표，비교량조간적각항지표。결과량조자궁내막후도급자궁내막류형비교차이무통계학의의（ P＞0.05）；임신조자궁내막유혈류소점비례[45.45％（30／66）]고우비임신조[25.25％（25／99）]（P＜0.05）；임신조자궁내막하혈류RI（0.30±0.05）저우비임신조（0.69±0.07）（P＜0.05）。결론경음도채초검측자궁내막혈류급자궁내막하혈류RI대IVF－ET결국유일정예측개치。
Objective To investigate the influence of uterine artery, endometrium and endometrial blood flow on the pregnancy outcomes of in vitro fertilization-embryo transfer ( IVF-ET) .Methods 165 patients underwent IVF-ET cycles in Anhui Province Maternity and Child Health Hospital from Jun 2010 to Jun 2012 were recruited, who were divided into pregnancy group ( n=66 ) and unpregnancy group ( n=99 ) according to pregnany outcomes.Transvaginal color Doppler sonography ( TV-CDS ) examination was performed to determine endometrial thickness, endometrial pattern on human chorionic gonadotropin ( HCG ) day, injection and systolic/diastolic ratio (S/D), resisitance index (RI), pulsatility index (PI), endometrium and endometrial blood flow on ET day, the indicators of two groups were compared.Results The differences of endometrial thickness and endometrial pattern between two groups had no significant difference (P>0.05) .The proportion of endometrial blood flow in pregnancy group[45.45 %(30/66)] was significantly higher than that of unpregnancy group [ 25.25 %( 25/99 ) ] ( P <0.05 ) .The RI of endometrial blood flow in pregnancy group ( 0.30 ±0.05 ) was lower than that of unpregnancy group ( 0.69 ±0.07 ) ( P <0.05 ) .Conclusion Using endometrial blood flowand RI of subendometrial blood flow detected by TVS to predict the outcomes of IVF-ET is valuable.