心血管康复医学杂志
心血管康複醫學雜誌
심혈관강복의학잡지
JOURNAL OF CARDIOVASCULAR REHABILITATION MEDICINE
2015年
4期
388-390
,共3页
高血压性视网膜病变%心脏扩大%肾功能不全
高血壓性視網膜病變%心髒擴大%腎功能不全
고혈압성시망막병변%심장확대%신공능불전
Hypertensive retinopathy%Cardiomegaly%Renal insufficiency
目的:分析高血压视网膜病变(HRP)与高血压心脏改变及肾病的关系。方法:选择我院2012年1月至2013年12月诊治的100例高血压患者为研究对象,其中 HRP 者90例(HRPⅠ级34例、Ⅱ级49例、Ⅲ级6例、Ⅳ级1例),正常眼底10例(正常眼底组),分析所有患者临床资料,检测左心室重量指数(LVMI)、颈动脉内膜中层厚度(IMT)、肾小球滤过率(GFR)等指标。结果:与正常眼底组比较,HRPⅠ级+Ⅱ级组,Ⅲ级+Ⅳ级组 IMT [(0.62±0.30)mm比(0.87±0.16)mm 比(1.10±0.28)mm]显著增厚,Ⅲ级+Ⅳ级组的 IMT 较Ⅰ级+Ⅱ级组显著增厚(P 均<0.01);与正常眼底组比较,HRPⅠ级+Ⅱ级组,Ⅲ级+Ⅳ级组心脏扩大(0%比12.05%比71.43%)及肾脏功能损害(0%比24.10%比85.71%)发生率显著升高,Ⅲ级+Ⅳ级组的心脏扩大和肾脏功能损害发生率较Ⅰ级+Ⅱ级组显著升高(P均<0.01)。结论:高血压视网膜病变严重程度与高血压心脏扩大及肾脏功能损害有密切关系。
目的:分析高血壓視網膜病變(HRP)與高血壓心髒改變及腎病的關繫。方法:選擇我院2012年1月至2013年12月診治的100例高血壓患者為研究對象,其中 HRP 者90例(HRPⅠ級34例、Ⅱ級49例、Ⅲ級6例、Ⅳ級1例),正常眼底10例(正常眼底組),分析所有患者臨床資料,檢測左心室重量指數(LVMI)、頸動脈內膜中層厚度(IMT)、腎小毬濾過率(GFR)等指標。結果:與正常眼底組比較,HRPⅠ級+Ⅱ級組,Ⅲ級+Ⅳ級組 IMT [(0.62±0.30)mm比(0.87±0.16)mm 比(1.10±0.28)mm]顯著增厚,Ⅲ級+Ⅳ級組的 IMT 較Ⅰ級+Ⅱ級組顯著增厚(P 均<0.01);與正常眼底組比較,HRPⅠ級+Ⅱ級組,Ⅲ級+Ⅳ級組心髒擴大(0%比12.05%比71.43%)及腎髒功能損害(0%比24.10%比85.71%)髮生率顯著升高,Ⅲ級+Ⅳ級組的心髒擴大和腎髒功能損害髮生率較Ⅰ級+Ⅱ級組顯著升高(P均<0.01)。結論:高血壓視網膜病變嚴重程度與高血壓心髒擴大及腎髒功能損害有密切關繫。
목적:분석고혈압시망막병변(HRP)여고혈압심장개변급신병적관계。방법:선택아원2012년1월지2013년12월진치적100례고혈압환자위연구대상,기중 HRP 자90례(HRPⅠ급34례、Ⅱ급49례、Ⅲ급6례、Ⅳ급1례),정상안저10례(정상안저조),분석소유환자림상자료,검측좌심실중량지수(LVMI)、경동맥내막중층후도(IMT)、신소구려과솔(GFR)등지표。결과:여정상안저조비교,HRPⅠ급+Ⅱ급조,Ⅲ급+Ⅳ급조 IMT [(0.62±0.30)mm비(0.87±0.16)mm 비(1.10±0.28)mm]현저증후,Ⅲ급+Ⅳ급조적 IMT 교Ⅰ급+Ⅱ급조현저증후(P 균<0.01);여정상안저조비교,HRPⅠ급+Ⅱ급조,Ⅲ급+Ⅳ급조심장확대(0%비12.05%비71.43%)급신장공능손해(0%비24.10%비85.71%)발생솔현저승고,Ⅲ급+Ⅳ급조적심장확대화신장공능손해발생솔교Ⅰ급+Ⅱ급조현저승고(P균<0.01)。결론:고혈압시망막병변엄중정도여고혈압심장확대급신장공능손해유밀절관계。
Objective:To analyze the relationship among hypertensive cardiac change,kidney disease and hyperten-sive retinopathy (HRP).Methods:A total of 100 patients with hypertension,who were diagnosed and treated in our hospital from Jan 2012 to Dec 2013,were enrolled,including 90 HRP patients (34 cases of class Ⅰ,49 cases of class Ⅱ,six cases of class Ⅲ and one case of class Ⅳ)and 10 cases with normal fundus (normal control group). Clinical data of all patients were analyzed,left ventricular mass index (LVMI),carotid intima-media thickness (IMT)and glomerular filtration rate (GFR)etc.were measured.Results:Compared with normal control group, there were significant thickening in IMT [(0.62±0.30)mm vs.(0.87±0.16)mm vs.(1.10±0.28)mm]in HRP class Ⅰ+Ⅱ group,class Ⅲ+Ⅳ group,the IMT of class Ⅲ+Ⅳ group was significantly thickened than that of class Ⅰ+Ⅱ group (P <0.01 all);Compared with normal control group,the incidence rates of cardiac dilation (0%vs.12.05% vs.71.43%)and kidney function damage (0% vs.24.10% vs.85.71%)significantly rose in HRP class Ⅰ+Ⅱ group,class Ⅲ+Ⅳ group,the incidence rates of cardiac dilation and kidney function damage in HRP class Ⅲ+Ⅳ group significantly rose than those of class Ⅰ+Ⅱ group (P <0.01 all).Conclusion:Severity of hyper-tension retinopathy is closely related to hypertensive cardiac dilation and kidney function damage.