中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
22期
139-141,144
,共4页
原发性高血压%焦虑抑郁症%氟哌噻吨美利曲辛
原髮性高血壓%焦慮抑鬱癥%氟哌噻噸美利麯辛
원발성고혈압%초필억욱증%불고새둔미리곡신
Primary hypertension%Anxiety depression%Flupentixol and melitracen
目的：探讨氟哌噻吨美利曲辛治疗原发性高血压合并焦虑忧郁症的临床效果。方法选取2013年8月~2014年9月在本院门诊及心内科病房治疗的80例高血压合并焦虑抑郁症患者，将其按随机数字表法分为对照组和实验组，各40例。对照组采用厄贝沙坦治疗，实验组采用厄贝沙坦+氟哌噻吨美利曲辛治疗，两组疗程均8周，观察两组治疗前后抑郁自评量表(SDS)和焦虑自评量表(SAS)评分及血压变化情况。结果治疗后，两组的血压均有明显下降，且实验组较对照组下降幅度更加明显(P<0.05)；治疗8周后，实验组的SDS、SAS评分均显著降低(P<0.05)，但对照组无明显变化(P跃0.05)，因此，实验组的SDS、SAS评分显著低于对照组(P<0.01)。结论氟哌噻吨美利曲辛治疗原发高血压合并焦虑抑郁症具有显著的效果。
目的：探討氟哌噻噸美利麯辛治療原髮性高血壓閤併焦慮憂鬱癥的臨床效果。方法選取2013年8月~2014年9月在本院門診及心內科病房治療的80例高血壓閤併焦慮抑鬱癥患者，將其按隨機數字錶法分為對照組和實驗組，各40例。對照組採用阨貝沙坦治療，實驗組採用阨貝沙坦+氟哌噻噸美利麯辛治療，兩組療程均8週，觀察兩組治療前後抑鬱自評量錶(SDS)和焦慮自評量錶(SAS)評分及血壓變化情況。結果治療後，兩組的血壓均有明顯下降，且實驗組較對照組下降幅度更加明顯(P<0.05)；治療8週後，實驗組的SDS、SAS評分均顯著降低(P<0.05)，但對照組無明顯變化(P躍0.05)，因此，實驗組的SDS、SAS評分顯著低于對照組(P<0.01)。結論氟哌噻噸美利麯辛治療原髮高血壓閤併焦慮抑鬱癥具有顯著的效果。
목적：탐토불고새둔미리곡신치료원발성고혈압합병초필우욱증적림상효과。방법선취2013년8월~2014년9월재본원문진급심내과병방치료적80례고혈압합병초필억욱증환자，장기안수궤수자표법분위대조조화실험조，각40례。대조조채용액패사탄치료，실험조채용액패사탄+불고새둔미리곡신치료，량조료정균8주，관찰량조치료전후억욱자평량표(SDS)화초필자평량표(SAS)평분급혈압변화정황。결과치료후，량조적혈압균유명현하강，차실험조교대조조하강폭도경가명현(P<0.05)；치료8주후，실험조적SDS、SAS평분균현저강저(P<0.05)，단대조조무명현변화(P약0.05)，인차，실험조적SDS、SAS평분현저저우대조조(P<0.01)。결론불고새둔미리곡신치료원발고혈압합병초필억욱증구유현저적효과。
Objective To explore the therapeutic effect of flupentixol and melitracen in the treatment of patients with primary hypertension combining with anxious depression. Methods 80 patient with primary hypertension and anxious depression in our hospital outpatient and cardiology ward from August 2013 to September 2014 were selected and evenly divided into control group and experimental group by random number talbe,40 cases in each group.In control group,irbesartan was provided,while in the experimental group, irbesartan plus flupentixol and melitracen was provided. The courses of treatment lasted 8 weeks.Scores of self-rating depression scale (SDS) and self-rating anxiety scale(SAS) and changes of blood pressure in the two groups before and after treatment was observed. Results After theray,blood pressure in the two groups was obviously decreased,and the experimental group than the control group decreased more obvious (P<0.05).8 weeks after treatment,scores of SDS and SAS after therapy in the experimental group was decreased significantly(P<0.05),but control group showed no statistically significant improvements(P>0.05).Therefore,the scores of SDS and SAS in experimental group was significantly lower than that of control group(P<0.01). Conclusion Flupentixol and melitracen can obtain a remarkable effect on treating primary hypertension combining with anxious depression.
