中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
22期
118-120
,共3页
慢性阻塞性肺疾病%域型呼吸衰竭%噻托溴铵%无创正压通气%临床疗效
慢性阻塞性肺疾病%域型呼吸衰竭%噻託溴銨%無創正壓通氣%臨床療效
만성조새성폐질병%역형호흡쇠갈%새탁추안%무창정압통기%림상료효
Chronic obstructive pulmonary disease%Type II respiratory failure%Tiotropium bromide%Non-invasive posi-tive pressure ventilation
目的：分析噻托溴铵联合无创正压通气治疗慢性阻塞性肺疾病急性加重合并Ⅱ型呼吸衰竭的临床效果。方法收集2010年2月~2014年2月在本院诊治的92例慢性阻塞性肺疾病急性加重合并Ⅱ型呼吸衰竭患者作为研究对象,将其随机分为观察组(46例)与对照组(46例)。所有患者均实施呼吸内科常规治疗,在此基础上,对照组给予患者无创正压通气治疗,观察组应用噻托溴铵与无创正压通气联合治疗。观察两组的治疗效果、住院时间、再次入院率和累计死亡率。结果观察组患者的治疗总有效率为95.65%,显著高于对照组的80.43%,差异有统计学意义(P<0.05)。观察组患者的住院时间为(11.24±3.41)d,显著短于对照组的(16.44±4.12)d(P<0.05)。观察组患者的再次入院率、累计死亡率分别为21.74%、0%,均显著低于对照组(P<0.05)。结论慢性阻塞性肺疾病急性加重合并Ⅱ型呼吸衰竭治疗中应用噻托溴铵与无创正压通气联合治疗具有良好的临床效果,患者预后良好。
目的：分析噻託溴銨聯閤無創正壓通氣治療慢性阻塞性肺疾病急性加重閤併Ⅱ型呼吸衰竭的臨床效果。方法收集2010年2月~2014年2月在本院診治的92例慢性阻塞性肺疾病急性加重閤併Ⅱ型呼吸衰竭患者作為研究對象,將其隨機分為觀察組(46例)與對照組(46例)。所有患者均實施呼吸內科常規治療,在此基礎上,對照組給予患者無創正壓通氣治療,觀察組應用噻託溴銨與無創正壓通氣聯閤治療。觀察兩組的治療效果、住院時間、再次入院率和纍計死亡率。結果觀察組患者的治療總有效率為95.65%,顯著高于對照組的80.43%,差異有統計學意義(P<0.05)。觀察組患者的住院時間為(11.24±3.41)d,顯著短于對照組的(16.44±4.12)d(P<0.05)。觀察組患者的再次入院率、纍計死亡率分彆為21.74%、0%,均顯著低于對照組(P<0.05)。結論慢性阻塞性肺疾病急性加重閤併Ⅱ型呼吸衰竭治療中應用噻託溴銨與無創正壓通氣聯閤治療具有良好的臨床效果,患者預後良好。
목적：분석새탁추안연합무창정압통기치료만성조새성폐질병급성가중합병Ⅱ형호흡쇠갈적림상효과。방법수집2010년2월~2014년2월재본원진치적92례만성조새성폐질병급성가중합병Ⅱ형호흡쇠갈환자작위연구대상,장기수궤분위관찰조(46례)여대조조(46례)。소유환자균실시호흡내과상규치료,재차기출상,대조조급여환자무창정압통기치료,관찰조응용새탁추안여무창정압통기연합치료。관찰량조적치료효과、주원시간、재차입원솔화루계사망솔。결과관찰조환자적치료총유효솔위95.65%,현저고우대조조적80.43%,차이유통계학의의(P<0.05)。관찰조환자적주원시간위(11.24±3.41)d,현저단우대조조적(16.44±4.12)d(P<0.05)。관찰조환자적재차입원솔、루계사망솔분별위21.74%、0%,균현저저우대조조(P<0.05)。결론만성조새성폐질병급성가중합병Ⅱ형호흡쇠갈치료중응용새탁추안여무창정압통기연합치료구유량호적림상효과,환자예후량호。
Objective To analyze the clinical effect of of tiotropium bromide combined with non-invasive positive pres-sure ventilation in the treatment of acute exacerbation of chronic obstructive pulmonary disease with type II respiratory failure. Methods 92 patients with acute exacerbation of chronic obstructive pulmonary disease with type II respiratory failure admitted into our hospital from February 2010 to 2014 February were collecteg as research object.They were randomly divided into Observation group (46 cases) and control group (46 cases).All patients were received the conven-tional treatment of respiratory department of internal medicine,on this base the control group was received noninvasive positive pressure ventilation.In the observation group was received tiotropium bromide with noninvasive positive pres-sure ventilation combined treatment.The overall treatment effect,hospital stay,readmission rate and cumulative mortality in two groups was observed. Results The total effective rate of observation group was 95.65%,significantly higher than 80.43% of control group,there was statistical significance (P<0.05).The average length of stay in observation group was (11.24±3.41) d,significantly shorter than that of control group[(16.44±4.12)] d(P<0.05).The readmission rate and cumu-lative mortality rate in observation group respectively was 21.74%、0%,significantly lower than that of control group(P<0.05). Conclusion The combined treatment of tiotropium bromide and non-invasive positive pressure ventilation has good clinical efficacy in the treatment of acute exacerbation of chronic obstructive pulmonary disease with type II res-piratory failure,patients with good prognosis.
