中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2015年
7期
840-845
,共6页
杨鸿兵%周淑芹%曹宝卿%魏丹丹%蔡姬娜%陈静
楊鴻兵%週淑芹%曹寶卿%魏丹丹%蔡姬娜%陳靜
양홍병%주숙근%조보경%위단단%채희나%진정
脂肪肝%骨密度%骨质疏松%身高体重指数%肥胖
脂肪肝%骨密度%骨質疏鬆%身高體重指數%肥胖
지방간%골밀도%골질소송%신고체중지수%비반
Fatty liver%BMD%Osteoporosis%Body mass index%Obesity
目的:探讨脂肪肝与骨密度间的变化规律及关系。方法选自2013年在我院进行B超检查和骨密度测量的体检人群,共计1014例。以B超诊断脂肪肝为标准:脂肪肝组469例,男性370例、女性99例;非脂肪肝组545例,男性282例、女性263例。以BMI≥25kg/m2及BMI<25 kg/m2为标准:肥胖组465例、男345例、女120例;非肥胖组549例,男307例、女242例。年龄20~85岁,平均49.8岁。按男、女性别,每十岁年龄段分为脂肪肝和非脂肪肝组、肥胖组和非肥胖组,分别计算各组、各年龄段骨密度和BMI。利用SPSS19.0统计软件对数据进行处理分析,计量资料采用xˉ±s方式表示,两变量间相关性采用Pearson乘积-距相关分析,两组数据之间比较用独立样本T检验,P <0.05为差异有统计学意义。结果男性40-60岁,女性40-70岁脂肪肝组BMD高于非脂肪肝组BMD( P <0.05),脂肪肝组的骨量丢失低于非脂肪肝组;男性20-70、女性30-70脂肪肝组BMI高于非脂肪肝组BMI(P<0.05),由Pearson乘积-距相关分析,P <0.0001,脂肪肝与肥胖之间存在的直线相关关系具有统计学意义,两者正相关;男性20-60岁,女性40、50、70岁年龄段肥胖组BMD高于非肥胖组( P <0.05),肥胖组的骨量丢失低于非肥胖组;各组男女峰值骨量在30岁年龄段,40岁开始丢失,男性肥胖组峰值骨量高于非肥胖组( P<0.05)。有统计学意义的男女各年龄段,脂肪肝组和肥胖组骨量减低发病率明显低于非脂肪肝组和非肥胖组。脂肪肝组和肥胖组发病率接近,非脂肪肝组和非肥胖组的发病率接近。结论脂肪肝与骨密度间可能通过BMI存在一定的影响关系,BMI对脂肪肝的影响明确,对骨密度的影响尚不明确,可能存在阈值,有必要进一步深入研究。
目的:探討脂肪肝與骨密度間的變化規律及關繫。方法選自2013年在我院進行B超檢查和骨密度測量的體檢人群,共計1014例。以B超診斷脂肪肝為標準:脂肪肝組469例,男性370例、女性99例;非脂肪肝組545例,男性282例、女性263例。以BMI≥25kg/m2及BMI<25 kg/m2為標準:肥胖組465例、男345例、女120例;非肥胖組549例,男307例、女242例。年齡20~85歲,平均49.8歲。按男、女性彆,每十歲年齡段分為脂肪肝和非脂肪肝組、肥胖組和非肥胖組,分彆計算各組、各年齡段骨密度和BMI。利用SPSS19.0統計軟件對數據進行處理分析,計量資料採用xˉ±s方式錶示,兩變量間相關性採用Pearson乘積-距相關分析,兩組數據之間比較用獨立樣本T檢驗,P <0.05為差異有統計學意義。結果男性40-60歲,女性40-70歲脂肪肝組BMD高于非脂肪肝組BMD( P <0.05),脂肪肝組的骨量丟失低于非脂肪肝組;男性20-70、女性30-70脂肪肝組BMI高于非脂肪肝組BMI(P<0.05),由Pearson乘積-距相關分析,P <0.0001,脂肪肝與肥胖之間存在的直線相關關繫具有統計學意義,兩者正相關;男性20-60歲,女性40、50、70歲年齡段肥胖組BMD高于非肥胖組( P <0.05),肥胖組的骨量丟失低于非肥胖組;各組男女峰值骨量在30歲年齡段,40歲開始丟失,男性肥胖組峰值骨量高于非肥胖組( P<0.05)。有統計學意義的男女各年齡段,脂肪肝組和肥胖組骨量減低髮病率明顯低于非脂肪肝組和非肥胖組。脂肪肝組和肥胖組髮病率接近,非脂肪肝組和非肥胖組的髮病率接近。結論脂肪肝與骨密度間可能通過BMI存在一定的影響關繫,BMI對脂肪肝的影響明確,對骨密度的影響尚不明確,可能存在閾值,有必要進一步深入研究。
목적:탐토지방간여골밀도간적변화규률급관계。방법선자2013년재아원진행B초검사화골밀도측량적체검인군,공계1014례。이B초진단지방간위표준:지방간조469례,남성370례、녀성99례;비지방간조545례,남성282례、녀성263례。이BMI≥25kg/m2급BMI<25 kg/m2위표준:비반조465례、남345례、녀120례;비비반조549례,남307례、녀242례。년령20~85세,평균49.8세。안남、녀성별,매십세년령단분위지방간화비지방간조、비반조화비비반조,분별계산각조、각년령단골밀도화BMI。이용SPSS19.0통계연건대수거진행처리분석,계량자료채용xˉ±s방식표시,량변량간상관성채용Pearson승적-거상관분석,량조수거지간비교용독립양본T검험,P <0.05위차이유통계학의의。결과남성40-60세,녀성40-70세지방간조BMD고우비지방간조BMD( P <0.05),지방간조적골량주실저우비지방간조;남성20-70、녀성30-70지방간조BMI고우비지방간조BMI(P<0.05),유Pearson승적-거상관분석,P <0.0001,지방간여비반지간존재적직선상관관계구유통계학의의,량자정상관;남성20-60세,녀성40、50、70세년령단비반조BMD고우비비반조( P <0.05),비반조적골량주실저우비비반조;각조남녀봉치골량재30세년령단,40세개시주실,남성비반조봉치골량고우비비반조( P<0.05)。유통계학의의적남녀각년령단,지방간조화비반조골량감저발병솔명현저우비지방간조화비비반조。지방간조화비반조발병솔접근,비지방간조화비비반조적발병솔접근。결론지방간여골밀도간가능통과BMI존재일정적영향관계,BMI대지방간적영향명학,대골밀도적영향상불명학,가능존재역치,유필요진일보심입연구。
Objective To investigate the changes and relationship between fatty liver and bone mineral density.Methods A total of 1014 healthy screen people who had B-ultrasound examination and BMD measurement in our hospital in 2013 were selected. According to B-ultrasound standard of fatty liver, 469 cases were divided to fatty liver group, including 370 males and 99 females, and 549 cases were divided to non-fatty liver group, including 307 males and 242 females.According to BMI, 465 cases were divided to obese group ( BMI≥25 kg/m2 ) , including 345 males and 120 females, and 549 cases were divided to non-obese group ( BMI<25 kg/m2 ) , including 307 males and 242 females.They were 20-85 years old, with an average of 49.8 years old.Fatty liver and non-fatty liver group, obese and non-obese group were divided by gender and every 10-year-old of age.BMD and BMI of each group were calculated.Data were processed and analyzed with SPSS 19.0 software.The measurement data were represented as xˉ±s.The correlation between the two variables was performed using Pearson correlation analysis.Data between the two groups were compared with independent sample t-test, and P<0.05 represented the difference was statistically significant.Results The BMD in fatty liver was higher than that in non-fatty liver group of 40-60-year-old males and 40-70-year-old females ( P<0.05), and the boss lose in fatty liver was lower than that in non-fatty liver group.BMI in fatty liver was higher than that in non-fatty liver group of 20-70-year-old males and 30-70-year-old females ( P<0.05 ) .Pearson correlation analysis showed that fatty liver was positively and linearly correlated with obesity (P<0.0001), with statistical significance.BMD in obese group was higher than that in non-obese group of 20-60-year-old males and 40-, 50-, and 70-year-old females.The boss lose in obese group was lower than that in non-obese group.The peak bone mass in each group of males and females appeared in 30-year group, and it began to lose on 40 years old.The peak bone mass of males in obese group was higher than that in non-obese group ( P<0.05).The incidence of osteopenia was significant lower in fatty liver group and obese group than that in non-fatty liver group and in non-obese group.The incidence in fatty liver group was close to that in obese group, and it was close in non-fatty liver group and in non-obese group.Conclusion Fatty liver may affect BMD through BMI.The effect of BMI on fatty liver was clear, but the effect on BMD is not clear.There may be a threshold existing.It is necessary to study further.