CAJ | 학술논문

目的：探讨拉坦前列素对开角型青光眼眼压及血流动力学的影响。方法：选择2014年2月-2015年1月来笔者所在医院进行治疗的开角型青光眼患者100例，按照患者入院顺序分为观察组和对照组，每组50例患者。观察组患者采用拉坦前列素进行治疗，对照组患者则采用噻吗心安治疗。结果：两组患者治疗后眼压明显下降，且观察组患者在治疗各阶段眼压均低于对照组，与对照组比较差异有统计学意义(P<0.05)；两组患者治疗后PSV、EDV均有所增加，RI明显的减小；观察组在治疗后CRA、PCA各项血流动力学指标与治疗前相比差异有统计学意义(P<0.05)。结论：拉坦前列素能有效改善患者眼压及相关血流动力学，是理想的抗青光眼药物。
목적：탐토랍탄전렬소대개각형청광안안압급혈류동역학적영향。방법：선택2014년2월-2015년1월래필자소재의원진행치료적개각형청광안환자100례，안조환자입원순서분위관찰조화대조조，매조50례환자。관찰조환자채용랍탄전렬소진행치료，대조조환자칙채용새마심안치료。결과：량조환자치료후안압명현하강，차관찰조환자재치료각계단안압균저우대조조，여대조조비교차이유통계학의의(P<0.05)；량조환자치료후PSV、EDV균유소증가，RI명현적감소；관찰조재치료후CRA、PCA각항혈류동역학지표여치료전상비차이유통계학의의(P<0.05)。결론：랍탄전렬소능유효개선환자안압급상관혈류동역학，시이상적항청광안약물。
Objective:To investigate the effect of Latanoprost on open angle glaucoma intraocular pressure and hemodynamics.Method:100 cases with open angle glaucoma were selected in our hospital for treatment from February 2014 to January 2015,according to the patients order,they were divided into the observation group and the control group,each group of 50 cases.The observation group was treated with Latanoprost,the control group was treated with Timolol.Result:After treatment,intraocular pressure decreased significantly in two groups,and the patients in the observation group were lower than those in the control group in the treatment of various stages of intraocular pressure,there were statistical significant in two groups(P<0.05);the patients in the two groups after treatment PSV,EDV increased,RI reduced apparently;in the observation group after treatment,the hemodynamic index of CRA and PCA compared with those before treatment there were significant differences(P<0.05).Conclusion:Latanoprost can effectively improve the patients with intraocular pressure and hemodynamic,which is the ideal anti glaucoma drugs.