中华现代护理杂志
中華現代護理雜誌
중화현대호리잡지
CHINESE JOURNAL OF MODERN NURSING
2015年
23期
2752-2755
,共4页
刘健%王建元%蒋珍玉%邓立华
劉健%王建元%蔣珍玉%鄧立華
류건%왕건원%장진옥%산립화
职业病%慢性苯中毒%医院感染%危险因素
職業病%慢性苯中毒%醫院感染%危險因素
직업병%만성분중독%의원감염%위험인소
Occupational disease%Chronic Benzene poisoning%Nosocomial infection%Risk factors
目的:探讨引起职业性慢性苯中毒患者医院感染的危险因素,为有效做好慢性苯中毒患者的医院感染控制与管理工作提供理论依据。方法对深圳市职业病防治院职业病科2006年7月—2014年6月收治的222例慢性苯中毒病例进行回顾性调查,其中63例为医院感染组,159例无任何感染者为非医院感染组,对两组资料进行单因素分析后,进行非条件Logistic二元回归分析。结果8年共发生医院感染63例,医院感染的发生率为28.37%,感染例次数为87,例次发病率为39.19%;感染部位以呼吸道为主,占42.53%。多因素分析得出差异有统计学意义的因素有6项,分别为:外周血白细胞计数(OR=1.515,P<0.01,95%CI:1.419~1.618)、中性粒细胞(OR =0.006,P <0.01,95%CI:0.002~0.014)、血小板(OR=0.891,P<0.01,95%CI:0.862~0.921)、诊断分级(OR=1.271,P<0.01,95%CI:1.208~1.338)、住院时间(OR=5.907,P<0.01,95%CI:5.645~6.181)和文化程度(OR=0.532,P<0.01,95%CI:0.480~0.589)。结论慢性苯中毒患者医院感染率高,住院时间、外周血白细胞计数、诊断分级是慢性苯中毒发生医院感染的独立危险因素,中性粒细胞、文化程度、血小板为其保护性因素。
目的:探討引起職業性慢性苯中毒患者醫院感染的危險因素,為有效做好慢性苯中毒患者的醫院感染控製與管理工作提供理論依據。方法對深圳市職業病防治院職業病科2006年7月—2014年6月收治的222例慢性苯中毒病例進行迴顧性調查,其中63例為醫院感染組,159例無任何感染者為非醫院感染組,對兩組資料進行單因素分析後,進行非條件Logistic二元迴歸分析。結果8年共髮生醫院感染63例,醫院感染的髮生率為28.37%,感染例次數為87,例次髮病率為39.19%;感染部位以呼吸道為主,佔42.53%。多因素分析得齣差異有統計學意義的因素有6項,分彆為:外週血白細胞計數(OR=1.515,P<0.01,95%CI:1.419~1.618)、中性粒細胞(OR =0.006,P <0.01,95%CI:0.002~0.014)、血小闆(OR=0.891,P<0.01,95%CI:0.862~0.921)、診斷分級(OR=1.271,P<0.01,95%CI:1.208~1.338)、住院時間(OR=5.907,P<0.01,95%CI:5.645~6.181)和文化程度(OR=0.532,P<0.01,95%CI:0.480~0.589)。結論慢性苯中毒患者醫院感染率高,住院時間、外週血白細胞計數、診斷分級是慢性苯中毒髮生醫院感染的獨立危險因素,中性粒細胞、文化程度、血小闆為其保護性因素。
목적:탐토인기직업성만성분중독환자의원감염적위험인소,위유효주호만성분중독환자적의원감염공제여관리공작제공이론의거。방법대심수시직업병방치원직업병과2006년7월—2014년6월수치적222례만성분중독병례진행회고성조사,기중63례위의원감염조,159례무임하감염자위비의원감염조,대량조자료진행단인소분석후,진행비조건Logistic이원회귀분석。결과8년공발생의원감염63례,의원감염적발생솔위28.37%,감염례차수위87,례차발병솔위39.19%;감염부위이호흡도위주,점42.53%。다인소분석득출차이유통계학의의적인소유6항,분별위:외주혈백세포계수(OR=1.515,P<0.01,95%CI:1.419~1.618)、중성립세포(OR =0.006,P <0.01,95%CI:0.002~0.014)、혈소판(OR=0.891,P<0.01,95%CI:0.862~0.921)、진단분급(OR=1.271,P<0.01,95%CI:1.208~1.338)、주원시간(OR=5.907,P<0.01,95%CI:5.645~6.181)화문화정도(OR=0.532,P<0.01,95%CI:0.480~0.589)。결론만성분중독환자의원감염솔고,주원시간、외주혈백세포계수、진단분급시만성분중독발생의원감염적독립위험인소,중성립세포、문화정도、혈소판위기보호성인소。
Objective To study the risk factors that lead to nosocomial infection of occupational chronic Benzene poisoning patients, and can provide theoretical foundation for infection control and management of occupational chronic Benzene poisoning patients. Methods A retrospective review was made among 222 cases of chronic Benzene poisoning patients who were hospitalized in Occupational Diseases Department in Shenzhen Prevertion and Treatment Center for Occupational Disease during the period between July 2006 and June 2014. A total of 63 cases were nosocomial infection group while 159 cases were non-infected group, and the patients of two groups were analyzed by single factor analysis and logistic repression analysis. Results There were 63 nosocomial infection cases during 8 years that the rate of nosocomial infection was 28. 37%. There were 87 infection samples with the rate 39. 19%;the most common infection site was respiratory tract accounting for 42. 53%. After logistic repression analysis, we obtained 6 risk factors which differences were statistically significant including WBC count (OR=1. 515,P<0. 01,95%CI:1. 419-1. 618), neutrophil (OR=0. 006,P<0. 01,95%CI:0. 002-0. 014), soterocyte (OR=0. 891,P<0. 01,95%CI:0. 862-0. 921), diagnosis grading (OR=1. 271,P<0. 01,95%CI:1. 208-1. 338), length of stay (OR=5. 907,P<0. 01,95%CI:5. 645-6. 181) and education degree (OR = 0. 532,P < 0. 01,95% CI:0. 480-0. 589). Conclusions Chronic Benzene poisoning has a high nosocomial infection rate, and the length of hospitalization, WBC count and diagnosis grading, that all are independent risk factors of nosocomial infection for chronic Benzene poisoning patients while neutrophil, education degree and soterocyte are protective factors.