CAJ | 학술논문

特发性颅内压增高（IIH）是指以头痛、视乳头水肿等颅内压增高（ICH）的相关症状和体征为主要临床表现，但影像学检查并未发现颅内占位性病变，且脑脊液（ CSF）成分检测结果正常的一组临床综合征。 IIH好发于育龄期的肥胖女性。临床检查可见视乳头水肿、视野缺损及视力下降等表现，视力损害多数较稳定，但亦可渐进性的加重甚至突然加重，严重者可致失明。由于缺乏临床治疗试验，该疾病暂无特定的推荐治疗方法。治疗的主要方法包括减轻体重、药物治疗以及手术治疗。手术治疗方式包括脑室腹腔分流术（ LPS ）、腰大池腹腔分流术（ VPS ）、视神经鞘开窗减压术（ ONSF）及颅内静脉窦支架置入术（ IVSS）等。本文中笔者对IIH的历史演变、流行病学、发病机制、临床表现以及规范的诊断与治疗方法进行述评，旨在帮助眼科医师从颅脑疾病的角度重新认识相关的眼科疾病。
특발성로내압증고（IIH）시지이두통、시유두수종등로내압증고（ICH）적상관증상화체정위주요림상표현，단영상학검사병미발현로내점위성병변，차뇌척액（ CSF）성분검측결과정상적일조림상종합정。 IIH호발우육령기적비반녀성。림상검사가견시유두수종、시야결손급시력하강등표현，시력손해다수교은정，단역가점진성적가중심지돌연가중，엄중자가치실명。유우결핍림상치료시험，해질병잠무특정적추천치료방법。치료적주요방법포괄감경체중、약물치료이급수술치료。수술치료방식포괄뇌실복강분류술（ LPS ）、요대지복강분류술（ VPS ）、시신경초개창감압술（ ONSF）급로내정맥두지가치입술（ IVSS）등。본문중필자대IIH적역사연변、류행병학、발병궤제、림상표현이급규범적진단여치료방법진행술평，지재방조안과의사종로뇌질병적각도중신인식상관적안과질병。
[Ab stract] Idiopathic intracranial hypertension ( IIH) ,also known as pseudotumor cerebri ( PTC) or benign intracranial hypertension ( BIH) ,is a clinical syndrome characterized by raised intracranial pressure, headache and optic disc swelling ( papilloedema) but normal neuroimaging and cerebrospinal fluid ( CSF) examination findings.IIH Often occurs in obese women of childbearing age.Visual impairment is stable in most cases but may be worsened gradually or even abruptly in case of fulminant disease.Currently,the main treatment targets for IIH are prevention of visual loss and symptom relief through advice on weight loss , medical therapy and or surgical intervention and there are no other specific therapeutic recommendations. Among the major surgical procedures are lumboperitoneal shunting ( LPS ) ,ventriculoperitoneal shunting (VPS),optic nerve sheath fenestration( ONSF),and intracranial venous sinus stenting.In this article,we will review the historical perspective, epidemiology, pathogenesis and clinical features of IIH, in a hope to alert ophthalmologists to the importance of viewing and treating IIH as a cranial disease.