CAJ | 학술논문

艾塞那肽是一种胰高血糖素样肽1拟似物，可促进胰岛素分泌，减少葡萄糖释放，减慢食物吸收和延缓胃排空，从而降低体质量和餐后血糖。二甲双胍是治疗2型糖尿病的一线药物，可降低2型糖尿病患者的血糖、糖化血红蛋白和体质指数等。研究及临床观察表明，大多数2型糖尿病患者均需接受药物联合治疗。目前，艾塞那肽联合二甲双胍治疗2型糖尿病已成为热点。
애새나태시일충이고혈당소양태1의사물，가촉진이도소분비，감소포도당석방，감만식물흡수화연완위배공，종이강저체질량화찬후혈당。이갑쌍고시치료2형당뇨병적일선약물，가강저2형당뇨병환자적혈당、당화혈홍단백화체질지수등。연구급림상관찰표명，대다수2형당뇨병환자균수접수약물연합치료。목전，애새나태연합이갑쌍고치료2형당뇨병이성위열점。
Exenatide is a kind of glucagon-like peptide which can increase insulin secretion , decrease glucagon release,reduce food intake,and slow gastric emptying,thus to promote weight loss and reduce the postprandial blood glucose.Metformin is the first-line drug for patients with type 2 diabetes,which can reduce the blood glucose,glycosylated hemoglobin,body mass index and weight.Researches and clinical observations showed that most patients with type 2 diabetes need combined drug therapy.Combination of exenatide and metformin in treatment of type 2 diabetes has become a current hotspot.