中华妇幼临床医学杂志（电子版）
中華婦幼臨床醫學雜誌（電子版）
중화부유림상의학잡지（전자판）
CHINESE JOURNAL OF OBSTETRICS & GYNECOLOGY AND PEDIATRICS(ELECTRONIC VERSION)
2015年
4期
530-534
,共5页
陈文科%侯昉(综述)%刘文英(审校)
陳文科%侯昉(綜述)%劉文英(審校)
진문과%후방(종술)%류문영(심교)
疝,横膈%病因%诊断%治疗%预后%随访研究
疝,橫膈%病因%診斷%治療%預後%隨訪研究
산,횡격%병인%진단%치료%예후%수방연구
Hernia,diaphragmatic%Pathogenesis%Diagnosis%Treatment%Prognosis%Follow-up studies
先天性膈疝(CDH)是膈肌异常伴随肺发育不良(PH)、新生儿持续肺动脉高压(PPHN)等病理、生理改变的先天性疾病,其发病率、病死率均较高。迄今为止,CDH 的具体病因、最佳治疗措施及预后影响因素均未阐明,这使得 CDH 的诊治具有挑战性。近年由于医学技术的不断进步、各种治疗措施的不断改进,CDH 患儿的存活率有所提高。然而,CDH 存活患儿的长期跟踪随访,尚需引起临床医师的足够重视,包括如何改善其预后、提高生活质量等。笔者拟就 CDH 的最新诊治进展,进行综述如下。
先天性膈疝(CDH)是膈肌異常伴隨肺髮育不良(PH)、新生兒持續肺動脈高壓(PPHN)等病理、生理改變的先天性疾病,其髮病率、病死率均較高。迄今為止,CDH 的具體病因、最佳治療措施及預後影響因素均未闡明,這使得 CDH 的診治具有挑戰性。近年由于醫學技術的不斷進步、各種治療措施的不斷改進,CDH 患兒的存活率有所提高。然而,CDH 存活患兒的長期跟蹤隨訪,尚需引起臨床醫師的足夠重視,包括如何改善其預後、提高生活質量等。筆者擬就 CDH 的最新診治進展,進行綜述如下。
선천성격산(CDH)시격기이상반수폐발육불량(PH)、신생인지속폐동맥고압(PPHN)등병리、생리개변적선천성질병,기발병솔、병사솔균교고。흘금위지,CDH 적구체병인、최가치료조시급예후영향인소균미천명,저사득 CDH 적진치구유도전성。근년유우의학기술적불단진보、각충치료조시적불단개진,CDH 환인적존활솔유소제고。연이,CDH 존활환인적장기근종수방,상수인기림상의사적족구중시,포괄여하개선기예후、제고생활질량등。필자의취 CDH 적최신진치진전,진행종술여하。
Congenital diaphragmatic hernia (CDH ) is an uncommon congenital anomaly of the diaphragm with pulmonary hypoplasia (PH)and persistent pulmonary hypertension as serious consequences (PPHN).Till now,the etiopathogenisis and best treatment strategies are still largely unknown,and practice strategies vary widely among different centres,so CDH still remains a challenging condition.In recent years,with the development of medical technology and improvement of treatment,survival rates of CDH patients appear to have increased.Survivors have been shown to be at risk for many long-term morbidities,so the importance of long-term follow-up of CDH survivals should be highlighted,including long-term prognosis and quality of life.This research focuses on the progress research of current diagnosis and treatment of CDH.
