CAJ | 학술논문

卵磷脂胆固醇酰基转移酶（ LCAT）是人体血浆脂蛋白代谢过程中起关键作用的一种酶，对维持胆固醇稳态、调节胆固醇在血液循环中的转运及胆固醇在外周组织中的清除有十分重要的作用。它能催化血浆中高密度脂蛋白（ HDL）游离胆固醇的酯化，参与胆固醇逆向转运，在 HDL的成熟代谢及动脉粥样硬化发生、发展过程中起重要作用，因此，对 LCAT的深入探讨和研究，有利于心血管疾病的防治。
란린지담고순선기전이매（ LCAT）시인체혈장지단백대사과정중기관건작용적일충매，대유지담고순은태、조절담고순재혈액순배중적전운급담고순재외주조직중적청제유십분중요적작용。타능최화혈장중고밀도지단백（ HDL）유리담고순적지화，삼여담고순역향전운，재 HDL적성숙대사급동맥죽양경화발생、발전과정중기중요작용，인차，대 LCAT적심입탐토화연구，유리우심혈관질병적방치。
Lecithin cholesterol acyltransferase(LCAT) plays a vital role in the metabolism of plasma lip-oproteins,which maintains cholesterol homeostasis, regulates cholesterol transport and removes cholesterol from peripheral tissue.It also plays a significant role in free cholesterol esterification of high-density lipopro-tein(HDL),cholesterol reverse transport,metabolism of HDL and the process of atherosclerosis.Therefore, the depth research of LCAT is helpful to the prevention and treatment of cardiovascular diseases .