CAJ | 학술논문

目的：探讨控制性低中心静脉压在肝癌切除术中对肝肾功能的影响。方法选取我院24例行肝叶切除术的原发性肝癌作为研究对象，采用数字随机法将患者分为控制性低中心静脉压组（ LCVP组）和正常中心静脉压组（ NCVP组），各12例，LCVP术中行控制性低中心静脉压（ CVP 0～5 cm H2 O），观察两组手术情况及肝、肾功能指标变化。结果24例患者手术均成功，两组病例在平均切肝时间、总手术时间无明显差异（P＞0．05）；LCVP组患者的失血量明显少于NCVP组，数据比较差异具有显著统计学意义（ P＜0．05）；两组患者术后7天AST、ALT、TP、TBIL、BUN、Cr与术前相比无明显差异，不具统计学意义（P＞0．05）。结论肝癌切除术中应用控制性低中心静脉压能够减少术中出血量，且对肝肾功能无明显影响。
목적：탐토공제성저중심정맥압재간암절제술중대간신공능적영향。방법선취아원24례행간협절제술적원발성간암작위연구대상，채용수자수궤법장환자분위공제성저중심정맥압조（ LCVP조）화정상중심정맥압조（ NCVP조），각12례，LCVP술중행공제성저중심정맥압（ CVP 0～5 cm H2 O），관찰량조수술정황급간、신공능지표변화。결과24례환자수술균성공，량조병례재평균절간시간、총수술시간무명현차이（P＞0．05）；LCVP조환자적실혈량명현소우NCVP조，수거비교차이구유현저통계학의의（ P＜0．05）；량조환자술후7천AST、ALT、TP、TBIL、BUN、Cr여술전상비무명현차이，불구통계학의의（P＞0．05）。결론간암절제술중응용공제성저중심정맥압능구감소술중출혈량，차대간신공능무명현영향。
Objective To study the control of central venous pressure effect on renal function in liver cancer resection.Methods Selected 24 routine lobe resection of primary liver cancer hospital as the research object, using the digital random method divided the patients into control group of low central venous pressure ( LCVP group) and normal central venous pressure ( NCVP group) , 12 cases, LCVP boc controlling center vein low voltage, observing two groups of operation conditions and index change of liver and kidneys, observing two groupsofoperationconditionandtheindexchangesofliverandkidneys.Results 24caseswereperformed successfully, two groups of cases in the mean time to cut the liver, total operation time has no obvious difference (P>0.05); LCVP group of patients with blood loss, RBC infusion quantity better than NCVP group, data comparison difference had statistical significance ( P<0.05); Two groups of postoperative 7 days AST, ALT, TP, TBIL, BUN, Cr no obvious difference compared with the preoperative, no statistical significance ( P>0. 05).Conclusions The application of controlled low central venous pressure liver cancer resection can reduce the intraoperative blood loss, and has no obvious effect on liver and kidney function.