中华临床医师杂志（电子版）
中華臨床醫師雜誌（電子版）
중화림상의사잡지（전자판）
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2015年
15期
2920-2925
,共6页
黄疸,阻塞性%肠道菌群失调%微生态制剂%粪菌移植
黃疸,阻塞性%腸道菌群失調%微生態製劑%糞菌移植
황달,조새성%장도균군실조%미생태제제%분균이식
Jaundice,obstructive%Intestinal dysbacteriosis%Probiotics%Fecal microbiota transplantation
梗阻性黄疸是临床上常见的病理状态，梗阻性黄疸患者术后高并发症发生率及死亡率一直是术后恢复过程中一大难题。目前，肠源性内毒素血症被认为是梗阻性黄疸预后不良的主要原因，而梗阻性黄疸时，致病菌大量繁殖，肠道菌群失调，内毒素移位是肠源性内毒素血症发生的主要机制。因此如何有效地控制梗阻性黄疸时的肠道菌群失调成为现今研究的热点。本文就梗阻性黄疸时肠道菌群的变化，如何进行干预，降低患者术后并发症的发生率及死亡率的最新进展进行综述，希望对梗阻性黄疸的治疗提供新的思路及对策。
梗阻性黃疸是臨床上常見的病理狀態，梗阻性黃疸患者術後高併髮癥髮生率及死亡率一直是術後恢複過程中一大難題。目前，腸源性內毒素血癥被認為是梗阻性黃疸預後不良的主要原因，而梗阻性黃疸時，緻病菌大量繁殖，腸道菌群失調，內毒素移位是腸源性內毒素血癥髮生的主要機製。因此如何有效地控製梗阻性黃疸時的腸道菌群失調成為現今研究的熱點。本文就梗阻性黃疸時腸道菌群的變化，如何進行榦預，降低患者術後併髮癥的髮生率及死亡率的最新進展進行綜述，希望對梗阻性黃疸的治療提供新的思路及對策。
경조성황달시림상상상견적병리상태，경조성황달환자술후고병발증발생솔급사망솔일직시술후회복과정중일대난제。목전，장원성내독소혈증피인위시경조성황달예후불량적주요원인，이경조성황달시，치병균대량번식，장도균군실조，내독소이위시장원성내독소혈증발생적주요궤제。인차여하유효지공제경조성황달시적장도균군실조성위현금연구적열점。본문취경조성황달시장도균군적변화，여하진행간예，강저환자술후병발증적발생솔급사망솔적최신진전진행종술，희망대경조성황달적치료제공신적사로급대책。
Obstructive jaundice is a common clinical pathology. High incidence of complications and mortality postoperatively of patients with obstructive jaundice have always been a big problem in the recovery process. At present, the intestinal endotoxemia is considered to be the main cause of poor prognosis of obstructive jaundice, and a large number of breeding bacteria, intestinal flora imbalance, endotoxin translocation are the main mechanism of happening of intestinal endotoxemia. Therefore, how to effectively control the intestinal dysbacteriosis caused by obstructive jaundice is becoming a hot spot of current research. This paper studied how to intervene the change of intestinal flora caused by obstructive jaundice for reducing the incidence of postoperative complications and mortality rate, to hope that new train of thought and countermeasures could be developed for the treatment of obstructive jaundice.
