齐齐哈尔医学院学报
齊齊哈爾醫學院學報
제제합이의학원학보
JOURNAL OF QIQIHAR MEDICAL COLLEGE
2015年
23期
3439-3441
,共3页
血清降钙素原%C反应蛋白%白介素-6%重症肺炎患者
血清降鈣素原%C反應蛋白%白介素-6%重癥肺炎患者
혈청강개소원%C반응단백%백개소-6%중증폐염환자
Serum procalcitonin%C -reactive protein%Interleukin -6%Patients with severe pneumonia
目的：探讨血清降钙素原（PCT）、C－反应蛋白（hs－CRP）及白细胞介素－6（IL－6）在重症肺炎患者中的含量变化及临床诊断意义。方法选取2014年1月至2015年1月于我院诊治的重症肺炎患者80例，以28 d为观察期，患者分为存活组41例和死亡组39例。检测两组患者血清中PCT、hs－CRP及IL－6水平，并行比较。结果死亡组PCT水平逐渐上升（ P＜0．05）；存活组PCT水平逐渐下降（P＜0．05）；死亡组PCT水平显著高于存活组（P＜0．05）。死亡组hs－CRP水平逐渐上升（P＜0．05）；存活组hs－CRP水平逐渐下降（P＜0．05）；死亡组hs－CRP水平显著高于存活组（P＜0．05）。死亡组IL－6水平逐渐上升（P＜0．05）；存活组IL－6水平逐渐下降（P＜0．05）；死亡组IL－6水平显著高于存活组（P＜0．05）。结论 PCT、hs－CRP及IL－6与重症肺炎患者疾病严重程度具有一定相关性，可作为临床诊治的指标。
目的：探討血清降鈣素原（PCT）、C－反應蛋白（hs－CRP）及白細胞介素－6（IL－6）在重癥肺炎患者中的含量變化及臨床診斷意義。方法選取2014年1月至2015年1月于我院診治的重癥肺炎患者80例，以28 d為觀察期，患者分為存活組41例和死亡組39例。檢測兩組患者血清中PCT、hs－CRP及IL－6水平，併行比較。結果死亡組PCT水平逐漸上升（ P＜0．05）；存活組PCT水平逐漸下降（P＜0．05）；死亡組PCT水平顯著高于存活組（P＜0．05）。死亡組hs－CRP水平逐漸上升（P＜0．05）；存活組hs－CRP水平逐漸下降（P＜0．05）；死亡組hs－CRP水平顯著高于存活組（P＜0．05）。死亡組IL－6水平逐漸上升（P＜0．05）；存活組IL－6水平逐漸下降（P＜0．05）；死亡組IL－6水平顯著高于存活組（P＜0．05）。結論 PCT、hs－CRP及IL－6與重癥肺炎患者疾病嚴重程度具有一定相關性，可作為臨床診治的指標。
목적：탐토혈청강개소원（PCT）、C－반응단백（hs－CRP）급백세포개소－6（IL－6）재중증폐염환자중적함량변화급림상진단의의。방법선취2014년1월지2015년1월우아원진치적중증폐염환자80례，이28 d위관찰기，환자분위존활조41례화사망조39례。검측량조환자혈청중PCT、hs－CRP급IL－6수평，병행비교。결과사망조PCT수평축점상승（ P＜0．05）；존활조PCT수평축점하강（P＜0．05）；사망조PCT수평현저고우존활조（P＜0．05）。사망조hs－CRP수평축점상승（P＜0．05）；존활조hs－CRP수평축점하강（P＜0．05）；사망조hs－CRP수평현저고우존활조（P＜0．05）。사망조IL－6수평축점상승（P＜0．05）；존활조IL－6수평축점하강（P＜0．05）；사망조IL－6수평현저고우존활조（P＜0．05）。결론 PCT、hs－CRP급IL－6여중증폐염환자질병엄중정도구유일정상관성，가작위림상진치적지표。
Objective To investigate level changes of Serum procalcitonin, C -reactive protein, interleukin-6 in patients with severe pneumonia, and its clinical diagnostic significance.Methods 80 cases of patients with severe pneumonia in our hospital from January 2014 to January 2015 were selected, and they were divided into survival group (41) and death group (39) based on 28 days observation period.The serum PCT, hs-CRP and IL-6 levels of two groups were detected and compared.Results The PCT level of death group was gradually decreased (P<0.05).The PCT level of survival group was gradually increased (P<0.05).The PCT level of death group was significantly higher than the survival group (P<0.05).The hs-CRP level of death group was gradually decreased (P<0.05).The hs-CRP level of survival group was gradually increased (P<0. 05).The hs-CRP level of death group was significantly higher than the survival group (P<0.05).The IL-6 level of death group was gradually decreased (P <0.05).The IL -6 level of survival group was gradually increased (P<0.05).The IL-6 level of death group was significantly higher than the survival group (P<0. 05).Conclusions PCT, hs -CRP and IL -6 levels were related to disease severity of patients with severe pneumonia, they can be used as diagnosis and treatment indicators.
