中国全科医学
中國全科醫學
중국전과의학
CHINESE GENERAL PRACTICE
2015年
20期
2418-2420
,共3页
蒋泽%史爱梅%戚文群%唐宝康
蔣澤%史愛梅%慼文群%唐寶康
장택%사애매%척문군%당보강
糖尿病,2型%血糖%C肽
糖尿病,2型%血糖%C肽
당뇨병,2형%혈당%C태
Diabetes mellitus,type 2%Blood glucose%C-peptide
目的：探讨空腹C肽（C0）、餐后2 hC肽（C2）与空腹C肽比值（C2/C0）与初诊2型糖尿病患者血糖波动的关系。方法选取2012年4月—2014年3月于泰州市第三人民医院内分泌科住院治疗的初诊2型糖尿病患者54例为研究对象。患者入院后测定C0、食用标准100 g馒头餐后2 hC肽（ C2）水平，佩戴动态葡萄糖监测系统进行动态血糖监测72 h，记录日间平均血糖（ MBG）、日间平均血糖波动幅度（ MAGE）、血糖标准差（ SDBG）、最大血糖波动幅度（ LAGE）。分别比较C0≥1.1μg/L和<1.1μg/L、C2/C0≥3.0和<3.0患者上述指标水平的差异。结果 C0<1.1μg/L患者MBG、MAGE、SDBG、LAGE高于C0≥1.1μg/L患者，差异有统计学意义（ P<0.05）。C2/C0<3.0患者MBG、MAGE、SDBG、LAGE高于C2/C0≥3.0患者，差异有统计学意义（ P<0.05）。结论 C0及C2/C0均能影响初诊2型糖尿病患者血糖波动，C0<1.1μg/L和C2/C0<3.0的患者血糖波动较大。
目的：探討空腹C肽（C0）、餐後2 hC肽（C2）與空腹C肽比值（C2/C0）與初診2型糖尿病患者血糖波動的關繫。方法選取2012年4月—2014年3月于泰州市第三人民醫院內分泌科住院治療的初診2型糖尿病患者54例為研究對象。患者入院後測定C0、食用標準100 g饅頭餐後2 hC肽（ C2）水平，珮戴動態葡萄糖鑑測繫統進行動態血糖鑑測72 h，記錄日間平均血糖（ MBG）、日間平均血糖波動幅度（ MAGE）、血糖標準差（ SDBG）、最大血糖波動幅度（ LAGE）。分彆比較C0≥1.1μg/L和<1.1μg/L、C2/C0≥3.0和<3.0患者上述指標水平的差異。結果 C0<1.1μg/L患者MBG、MAGE、SDBG、LAGE高于C0≥1.1μg/L患者，差異有統計學意義（ P<0.05）。C2/C0<3.0患者MBG、MAGE、SDBG、LAGE高于C2/C0≥3.0患者，差異有統計學意義（ P<0.05）。結論 C0及C2/C0均能影響初診2型糖尿病患者血糖波動，C0<1.1μg/L和C2/C0<3.0的患者血糖波動較大。
목적：탐토공복C태（C0）、찬후2 hC태（C2）여공복C태비치（C2/C0）여초진2형당뇨병환자혈당파동적관계。방법선취2012년4월—2014년3월우태주시제삼인민의원내분비과주원치료적초진2형당뇨병환자54례위연구대상。환자입원후측정C0、식용표준100 g만두찬후2 hC태（ C2）수평，패대동태포도당감측계통진행동태혈당감측72 h，기록일간평균혈당（ MBG）、일간평균혈당파동폭도（ MAGE）、혈당표준차（ SDBG）、최대혈당파동폭도（ LAGE）。분별비교C0≥1.1μg/L화<1.1μg/L、C2/C0≥3.0화<3.0환자상술지표수평적차이。결과 C0<1.1μg/L환자MBG、MAGE、SDBG、LAGE고우C0≥1.1μg/L환자，차이유통계학의의（ P<0.05）。C2/C0<3.0환자MBG、MAGE、SDBG、LAGE고우C2/C0≥3.0환자，차이유통계학의의（ P<0.05）。결론 C0급C2/C0균능영향초진2형당뇨병환자혈당파동，C0<1.1μg/L화C2/C0<3.0적환자혈당파동교대。
Objective To investigate the effects of fasting C -peptide( C0 )and the ratio of C2/C0 on the blood glucose fluctuation in newly diagnosed type 2 diabetic patients. Methods We enrolled 54 newly diagnosed type 2 diabetic patients who were admitted into the Department of Endocrinology of the Third People's Hospital of Taizhou in Jiangsu Province from April 2012 to March 2014. The C0 ,C2 after 100 g steamed bun intake,72 h dynamic blood glucose monitor by wearing dynamic blood glucose monitoring system,MBG,MAGE,SDBG and LAGE of the patients were tested. The above indicators were compared between the patients with C0≥1. 1 μg/L and patients with C0 <1. 1 μg/L and between patients with C2/C0≥3. 0 and patients with C2/C0 <3. 0. Results The patients with C0 <1. 1 μg/L were significantly higher(P <0. 05)than the patients with C0≥1. 1 μg/L in MBG,MAGE,SDBG and LAGE. The patients with C2/C0 <3. 0 were significantly higher( P<0. 05)than the patients with C2/C0≥3. 0 in MBG,MAGE,SDBG and LAGE. Conclusion Fasting C-peptide and the ratio of C2/C0 both have influence on blood glucose fluctuations in newly diagnosed type 2 diabetic patients. Patients with C0 <1. 1μg/L and C2/C0 <3. 0 have greater fluctution in blood glucose.
