CAJ | 학술논문

心脑血管疾病患者存在血管内皮功能不全，且血管内皮功能不全可能是病因以及疾患早期表现之一，而心脑血管疾患本身也加重血管内皮功能不全的发生。临床研究表明，正常的血管内皮具有保护作用，可以延缓心脑血管疾病的发生，且在发病早期，机体会出现内皮功能损伤。因此，及早进行血管内皮功能的检测并采取相应措施对心脑血管疾病的防治具有重要意义。当前，利用Endo-PAT设备可行无创血管内皮功能诊断，测定反应性充血指数在临床应用中具有重要意义。现对近年来有关血管内皮功能与反应性充血指数关系的研究作出总结，为其在临床上的更好应用提供参考依据。
심뇌혈관질병환자존재혈관내피공능불전，차혈관내피공능불전가능시병인이급질환조기표현지일，이심뇌혈관질환본신야가중혈관내피공능불전적발생。림상연구표명，정상적혈관내피구유보호작용，가이연완심뇌혈관질병적발생，차재발병조기，궤체회출현내피공능손상。인차，급조진행혈관내피공능적검측병채취상응조시대심뇌혈관질병적방치구유중요의의。당전，이용Endo-PAT설비가행무창혈관내피공능진단，측정반응성충혈지수재림상응용중구유중요의의。현대근년래유관혈관내피공능여반응성충혈지수관계적연구작출총결，위기재림상상적경호응용제공삼고의거。
Vascular endothelial dysfunction( VED) is the early manifestation in patients with cardiovascular and cerebrovascular dis-eases, furthermore cardiovascular disease and cerebrovascular disease itself also increase the occurrence of VED.Clinical researches show that normal vascular endothelium has protective effect, and can delay the occurrence of cardiovascular and cerebrovascular diseases, in the early stage, the body will appear endothelial dysfunction but no clinical symptoms.Therefore, early detection of vascular endothelial function and take corresponding measures to prevent cardiovascular disease have important significance.At present, the Endo-PAT equipment is used to detect vascular endothelial function noninvasively, and get the reactive hyperemia index which has important significance in clinical appli-cation.The research about the relationship between vascular endothelial function and reactive hyperemia index is summarized, which can provide reference for its clinical application.