CAJ | 학술논문

铁代谢异常可能通过多种途径参与肺动脉高压的发生发展。目前研究发现铁缺乏、铁代谢紊乱普遍存在于特发性肺动脉高压和遗传性肺动脉高压人群中。铁代谢异常既可能是肺动脉高压发生的原因，也可能成为肺动脉高压治疗的靶点。
철대사이상가능통과다충도경삼여폐동맥고압적발생발전。목전연구발현철결핍、철대사문란보편존재우특발성폐동맥고압화유전성폐동맥고압인군중。철대사이상기가능시폐동맥고압발생적원인，야가능성위폐동맥고압치료적파점。
Iron may involved in the development of pulmonary arterial hypertension from several different mechanisms.Evidence indi-cates that iron deficiency is prevalent in idiopathic and heritable forms of pulmonary arterial hypertension.Iron homeostasis disorder may be the reason of pulmonary arterial hypertension,and on the other hand,iron supplementation may be effective for pulmonary arterial hyperten-sion.