CAJ | 학술논문

目的：探讨慢性阻塞性肺疾病（ COPD ）急性加重期合并贫血患者的 BODE 指数变化。方法选择2010年5月至2013年1月江汉大学附属医院呼吸内科确诊的COPD急性加重期患者共273例。根据贫血标准分为两组，合并贫血的COPD患者（贫血组）40例，非贫血的COPD患者（非贫血组）随机选取40例。比较两组患者 BODE 指数，并对结果进行统计学分析。结果合并贫血的COPD患者发生率为14．6％，贫血组BODE指数高于非贫血组，差异有统计学意义（ P＜0．01）。其中体质指数、6 min步行试验距离、呼吸困难量表与非贫血组差异均有统计学意义（均 P＜0．01）；两组患者肺功能指标（ FEV1％，第1秒用力呼气容积占预计值百分比）比较差异无统计学意义（ P ＞0．05）。结论贫血可恶化COPD运动耐量，影响患者生活质量，预后更差。
목적：탐토만성조새성폐질병（ COPD ）급성가중기합병빈혈환자적 BODE 지수변화。방법선택2010년5월지2013년1월강한대학부속의원호흡내과학진적COPD급성가중기환자공273례。근거빈혈표준분위량조，합병빈혈적COPD환자（빈혈조）40례，비빈혈적COPD환자（비빈혈조）수궤선취40례。비교량조환자 BODE 지수，병대결과진행통계학분석。결과합병빈혈적COPD환자발생솔위14．6％，빈혈조BODE지수고우비빈혈조，차이유통계학의의（ P＜0．01）。기중체질지수、6 min보행시험거리、호흡곤난량표여비빈혈조차이균유통계학의의（균 P＜0．01）；량조환자폐공능지표（ FEV1％，제1초용력호기용적점예계치백분비）비교차이무통계학의의（ P ＞0．05）。결론빈혈가악화COPD운동내량，영향환자생활질량，예후경차。
Objective To study the changes of BODE indexes in patients with chronic obstructive pul-monary disease(COPD) complicated by anemia.Methods A total of 273 patients diagnosed as acute exac-erbation of COPD in Department of Respiratory Medicine,the Affiliated Hospital of Jianghan University from May 2010 to Jan.2013 were selected as research objects,according to the standard of anemia,the patients were divided into two groups,patients with anemia as anemia group(40 cases) and patients without anemic as non-anemia group(40 cases).BODE indexes of the two groups were compared and statistically analyzed. Results Incidence of anemia in patients with COPD was 14.6%,BODE indexes of the anemia group were higher than non-anemic group,there were statistically significant differences(P<0.01).Differences of BMI, 6MWD,and MMRC were statistically significant between the two groups(P<0.01),but difference of pulmo-nary function was not statistically significant between the two groups ( FEV1%,forced expiratory volume at the first second) ( P>0.05 ) .Conclusion Although the influence of anemia on pulmonary function in COPD patients has no statistically significant difference , anemia will worsen the COPD exercise tolerance , and impact on the quality of life in patients with poor prognosis .