CAJ | 학술논문

目的：通过分析2A型多发性内分泌腺瘤(MEN2A)的临床特点和治疗方法,提高对MEN2A的认识水平。方法回顾性分析我院2008~2015年收治的4例2A 型多发性内分泌腺瘤患者资料,分析临床治疗方法和效果。结果4例均行嗜铬细胞瘤切除,3例行甲状腺根治术,术后4例患者的MEN2A型症状均消失。结论手术是治疗该病的唯一方法,当嗜铬细胞瘤与甲状腺髓样癌同时存在时,应先尽快切除嗜铬细胞瘤。腹腔镜嗜铬细胞瘤切除术是治疗MEN2A中嗜铬细胞瘤的理想方法,该病易复发,再次手术难度大,但仍可行腹腔镜下原入路嗜铬细胞瘤切除术。
목적：통과분석2A형다발성내분비선류(MEN2A)적림상특점화치료방법,제고대MEN2A적인식수평。방법회고성분석아원2008~2015년수치적4례2A 형다발성내분비선류환자자료,분석림상치료방법화효과。결과4례균행기락세포류절제,3례행갑상선근치술,술후4례환자적MEN2A형증상균소실。결론수술시치료해병적유일방법,당기락세포류여갑상선수양암동시존재시,응선진쾌절제기락세포류。복강경기락세포류절제술시치료MEN2A중기락세포류적이상방법,해병역복발,재차수술난도대,단잉가행복강경하원입로기락세포류절제술。
Objective To improve the acknowledge of multiple endocrine neoplasia type IIA (MENIIA) by analyzing the clinical characteristics and treatments of MENIIA. Methods We reviewed the clinical data from 4 cases of MENIIA hospitalized from year 2008 to 2015. The clinical treatments and outcomes were analyzed. Results All 4 cases were underwent laparoscopic pheochromocytoma resection. 3 cases were underwent radical thyroidectomy. The MENIIA symptoms of all 4 cases were disappeared postoperation. Conclusion Surgical procedure is the only treatment for this disease. When pheochromocytoma and medullary thyroid carcinoma are coincidence,pheochromocytoma resection is suggested as soon as possible. Laparoscopic pheochromocytoma resection is the ideal method for pheochromocytoma in the MEN IIA. This disease has a high relapse rate and reoperation is difficult. But it is still feasible to do repeatedly laparoscopic pheochromocytoma resection by the original approach.