卒中与神经疾病
卒中與神經疾病
졸중여신경질병
2015年
4期
234-237
,共4页
骆志坚%熊念%王涛%向明清%涂强%黄毅%成祥林%王莉
駱誌堅%熊唸%王濤%嚮明清%塗彊%黃毅%成祥林%王莉
락지견%웅념%왕도%향명청%도강%황의%성상림%왕리
三七总皂苷%高血压性脑出血%血肿吸收%神经功能缺损
三七總皂苷%高血壓性腦齣血%血腫吸收%神經功能缺損
삼칠총조감%고혈압성뇌출혈%혈종흡수%신경공능결손
Panax notoginseng saponins%Hypertensive intracerebral hemorrhage%Absorption of he-matoma%Neurological deficit
目的：观察三七总皂苷(PNS)对高血压性脑出血(HICH )血肿吸收及神经功能恢复的影响。方法将入选的 HICH 患者120例随机分为 PNS 组(常规药物治疗加三七总皂苷)58例和对照组(常规药物治疗)62例；所有入选患者分别于入组第1、4、10、17 d利用 CT 测量血肿体积,并进行神经功能缺损评分(NIHSS)和日常生活活动能力评定(ADL)。对照组采用内科常规脑出血治疗方法,PNS 组先采用常规药物治疗3 d,并于第4 d开始加用血塞通注射液(主要成分为 PNS)0.4 g静滴,1次/d,连用14 d,于第10 d和第17 d进行疗效判定。结果PNS 组第10、17 d血肿体积均小于对照组(P <0.01)；第10 d神经功能缺损评分低于对照组(P <0.05),第17 d神经功能缺损评分低于对照组(P <0.01),日常生活活动能力分值均高于对照组(P<0.01)。结论三七总皂苷能明显促进高血压性脑出血血肿的吸收,促进神经功能的恢复。
目的：觀察三七總皂苷(PNS)對高血壓性腦齣血(HICH )血腫吸收及神經功能恢複的影響。方法將入選的 HICH 患者120例隨機分為 PNS 組(常規藥物治療加三七總皂苷)58例和對照組(常規藥物治療)62例；所有入選患者分彆于入組第1、4、10、17 d利用 CT 測量血腫體積,併進行神經功能缺損評分(NIHSS)和日常生活活動能力評定(ADL)。對照組採用內科常規腦齣血治療方法,PNS 組先採用常規藥物治療3 d,併于第4 d開始加用血塞通註射液(主要成分為 PNS)0.4 g靜滴,1次/d,連用14 d,于第10 d和第17 d進行療效判定。結果PNS 組第10、17 d血腫體積均小于對照組(P <0.01)；第10 d神經功能缺損評分低于對照組(P <0.05),第17 d神經功能缺損評分低于對照組(P <0.01),日常生活活動能力分值均高于對照組(P<0.01)。結論三七總皂苷能明顯促進高血壓性腦齣血血腫的吸收,促進神經功能的恢複。
목적：관찰삼칠총조감(PNS)대고혈압성뇌출혈(HICH )혈종흡수급신경공능회복적영향。방법장입선적 HICH 환자120례수궤분위 PNS 조(상규약물치료가삼칠총조감)58례화대조조(상규약물치료)62례；소유입선환자분별우입조제1、4、10、17 d이용 CT 측량혈종체적,병진행신경공능결손평분(NIHSS)화일상생활활동능력평정(ADL)。대조조채용내과상규뇌출혈치료방법,PNS 조선채용상규약물치료3 d,병우제4 d개시가용혈새통주사액(주요성분위 PNS)0.4 g정적,1차/d,련용14 d,우제10 d화제17 d진행료효판정。결과PNS 조제10、17 d혈종체적균소우대조조(P <0.01)；제10 d신경공능결손평분저우대조조(P <0.05),제17 d신경공능결손평분저우대조조(P <0.01),일상생활활동능력분치균고우대조조(P<0.01)。결론삼칠총조감능명현촉진고혈압성뇌출혈혈종적흡수,촉진신경공능적회복。
Objective To observe the effect of panax notoginseng saponins (PNS)on hematoma absorp-tion and neurological function recovery in patients with hypertensive intracerebral hemorrhage(HICH).Meth-ods The 120 HICH patients enrolled were randomly divided into two groups,PNS group (conventional drug treatment plus PNS)58 cases and the control group (conventional drug treatment)62 cases.Scanning hemato-ma volume by CT,the National Institutes of Health Stroke Scale (NIHSS)scores and activities of daily living (ADL),all the three methods were used on the 1 st,the 4th,the 10 th and the 1 7 th day.Conventional medi-cal treatment of cerebral hemorrhage was used in the control group.PNS group were treated with conventional drug therapy for three days,and on the fourth day plus XUESAITONG injection (with the main component of PNS)0.4 g infusion,1 times/d,for 14 days.At the 10 th and the 1 7 th day,efficacy was determined. Results Hematoma volume of PNS group was less than that of the control group at the 10 th and the 1 7 th day. Neurological deficit scores were lower, while activities of daily living scores were higher. Conclusions PNS can significantly promote the absorption of hematoma as well as the recovery of neurological function in patients with HICH.
