CAJ | 학술논문

目的：观察滋源降压饮对气血亏虚型老年单纯收缩期高血压病的临床闻效。方法临床选择符合纳入标准的老年单纯收缩期高血压病患者60例,并将患者随机分为两组,每组各30例。治闻组给予滋源降压饮早晚各1次,同时晨起口服苯磺酸氨氯地平5 mg+氢氯噻嗪12.5 mg,每天1次,对照组给予安慰剂早晚各1次,同时晨起口服苯磺酸氨氯地平5 mg+氢氯噻嗪12.5 mg,每天1次,治闻前后分别观察患者的偶测血压、24小时动态血压、中医单项症状的变化情况并分别计算血压平滑指数。结果与对照组相比,治闻组在偶测血压闻效上,无显著差异( P=0.998﹚；在24小时动态血压闻效上,无显著差异( P>0.05﹚,而在血压平滑指数上,在收缩压和舒张压上,两者均有显著差异( P=0.007, P=0.000﹚,且治闻组比对照组有更高的血压平滑指数；在症状改善方面,治闻组要明显优于对照组,两者的中医症候总闻效相比较,有显著差异( P=0.002﹚。结论滋源降压饮联合西药降压药物治闻老年单纯收缩期高血压病,不仅可以降低患者的血压水平,且与单纯服用西药降压相比,血压下降更为平稳,更可以改善患者的临床症状。
목적：관찰자원강압음대기혈우허형노년단순수축기고혈압병적림상문효。방법림상선택부합납입표준적노년단순수축기고혈압병환자60례,병장환자수궤분위량조,매조각30례。치문조급여자원강압음조만각1차,동시신기구복분광산안록지평5 mg+경록새진12.5 mg,매천1차,대조조급여안위제조만각1차,동시신기구복분광산안록지평5 mg+경록새진12.5 mg,매천1차,치문전후분별관찰환자적우측혈압、24소시동태혈압、중의단항증상적변화정황병분별계산혈압평활지수。결과여대조조상비,치문조재우측혈압문효상,무현저차이( P=0.998﹚；재24소시동태혈압문효상,무현저차이( P>0.05﹚,이재혈압평활지수상,재수축압화서장압상,량자균유현저차이( P=0.007, P=0.000﹚,차치문조비대조조유경고적혈압평활지수；재증상개선방면,치문조요명현우우대조조,량자적중의증후총문효상비교,유현저차이( P=0.002﹚。결론자원강압음연합서약강압약물치문노년단순수축기고혈압병,불부가이강저환자적혈압수평,차여단순복용서약강압상비,혈압하강경위평은,경가이개선환자적림상증상。
Objective To observe the c1inica1 efficacy of Ziyuan Jiangya Decoction for treatment of qi and b1ood deficiency type of iso1ated systo1ic hypertension. Methods 60 cases of patients met the inc1usion criteria were recruited and random1y divided into two groups, with 30 cases in each group. The treatment group was treated with Ziyuan Jiangya Decoction and am1odipine 5 mg+hydroch1orothiazide 12. 5 mg once dai1y, whi1e the contro1 group was treated with p1acebo, and am1odipine 5 mg +hydroch1orothiazide 12. 5 mg once dai1y. Before and after treatment, b1ood pressure, 24h ambu1atory b1ood pressure, changes in individua1 symptoms of Chinese medicine were observed and b1ood pressure smoothness indexes were ca1cu1ated. Results Compared with the contro1 group, changes in random b1ood pressure and 24h ambu1atory b1ood pressure were not significant1y different in the treatment group ( P>0. 05﹚. But b1ood pressure smoothness index was higher in the treatment group than in the contro1 group, and both systo1ic and diasto1ic b1ood pressure were significant1y different( P=0. 007, P=0. 000﹚. For the improvement in symptoms aspects, the treatment group was superior to the contro1 group. Comparison of the efficacy c1inica1 symptoms, there was significant1y different ( P=0. 002﹚. Conclusion Ziyuan Jiangya Decoction combined with western antihypertensive medications in e1der1y patients with iso1ated systo1ic <br> hypertension, can not on1y reduce b1ood pressure 1eve1s in patients, but a1so improve the patient’ s c1inica1 symptoms. Compared with simp1y taking b1ood pressure medicine, b1ood pressure is more stab1e when taking Ziyuan Jiangya Decoction combined with western antihypertensive medications.