中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2015年
17期
95-96
,共2页
视网膜光凝%0.1％双氯芬酸钠眼液%疼痛
視網膜光凝%0.1％雙氯芬痠鈉眼液%疼痛
시망막광응%0.1％쌍록분산납안액%동통
Retinal laser photocoagulation%Sodium diclofenac 0.1％%Pain
目的 观察0.1％双氯芬酸钠眼液对视网膜光凝过程中疼痛程度的影响.方法 将86例患者分为两组,A组45例患者患增殖性糖尿病视网膜病变,给予每周1次视网膜光凝术,共两次.B组41例患者患非增殖性糖尿病视网膜病变合并黄斑水肿,19例为双眼,22例为单眼,给予黄斑格栅样光凝,0.1％双氯芬酸钠眼液和0.9％氯化钠注射液视网膜光凝前30 rmin点眼.行两次激光光凝患者第1次和第2次随机应用不同药物.应用视觉模拟评分法(visual analogue scale,VAS)对疼痛反应进行评估,数据进行统计学分析.结果 A组患者90次光凝中85次(94％)出现疼痛,其中应用0.1％双氯芬酸钠眼液平均疼痛水平为44.2％,应用氯化钠注射液的患者平均疼痛水平为53.1％ (P=0.011).B组60次光凝中有16次(26.7％)出现疼痛,疼痛程度10％～ 60％不等,两组疼痛的程度与激光斑数量、激光光凝的能量无明显相关性.结论 0.1％双氯芬酸钠眼液可明显减轻视网膜光凝的疼痛程度.
目的 觀察0.1％雙氯芬痠鈉眼液對視網膜光凝過程中疼痛程度的影響.方法 將86例患者分為兩組,A組45例患者患增殖性糖尿病視網膜病變,給予每週1次視網膜光凝術,共兩次.B組41例患者患非增殖性糖尿病視網膜病變閤併黃斑水腫,19例為雙眼,22例為單眼,給予黃斑格柵樣光凝,0.1％雙氯芬痠鈉眼液和0.9％氯化鈉註射液視網膜光凝前30 rmin點眼.行兩次激光光凝患者第1次和第2次隨機應用不同藥物.應用視覺模擬評分法(visual analogue scale,VAS)對疼痛反應進行評估,數據進行統計學分析.結果 A組患者90次光凝中85次(94％)齣現疼痛,其中應用0.1％雙氯芬痠鈉眼液平均疼痛水平為44.2％,應用氯化鈉註射液的患者平均疼痛水平為53.1％ (P=0.011).B組60次光凝中有16次(26.7％)齣現疼痛,疼痛程度10％～ 60％不等,兩組疼痛的程度與激光斑數量、激光光凝的能量無明顯相關性.結論 0.1％雙氯芬痠鈉眼液可明顯減輕視網膜光凝的疼痛程度.
목적 관찰0.1％쌍록분산납안액대시망막광응과정중동통정도적영향.방법 장86례환자분위량조,A조45례환자환증식성당뇨병시망막병변,급여매주1차시망막광응술,공량차.B조41례환자환비증식성당뇨병시망막병변합병황반수종,19례위쌍안,22례위단안,급여황반격책양광응,0.1％쌍록분산납안액화0.9％록화납주사액시망막광응전30 rmin점안.행량차격광광응환자제1차화제2차수궤응용불동약물.응용시각모의평분법(visual analogue scale,VAS)대동통반응진행평고,수거진행통계학분석.결과 A조환자90차광응중85차(94％)출현동통,기중응용0.1％쌍록분산납안액평균동통수평위44.2％,응용록화납주사액적환자평균동통수평위53.1％ (P=0.011).B조60차광응중유16차(26.7％)출현동통,동통정도10％～ 60％불등,량조동통적정도여격광반수량、격광광응적능량무명현상관성.결론 0.1％쌍록분산납안액가명현감경시망막광응적동통정도.
Objective To evaluate the analgesic effect of sodium diclofenac 0.1％ on retinal laser photocoagulation.Methods Among the 86 patients,45 patients with proliferative diabetic retinopathy were treated by two sessions of panretinal photocoagulation (group A),and 41 patients with nonproliferative diabetic retinopathy underwent grid treatment of the posterior pole (19 bilaterally) (group B).Sodium diclofenac 0.1％ or sodium chloride 0.9％ drops were topically applied 30 minutes before laser treatment in a masked fashion.Patients who had two sessions were given the alternate drug in the second one.Pain level was evaluated immediately after laser treatment with the visual analogue scale (VAS).The results were statistically analyzed.Results Patients in group A had pain in 85/90 sessions (94％).The average pain level was 44.2％ with sodium diclofenac 0.1％ drops and 53.1％ with sodium chloride 0.9％ drops (P =0.011).Patients in group B had pain in only 16/60 sessions (26.7％),and the pain level ranged from 10％ to 60％ regardless of the kind of drops used.There was no correlation in either group between level of pain and average energy level used (160-380 mW).Conclusions Sodium diclofenac 0.1％ is useful for pain reduction and should be applied before panretinal photocoagulation.
