中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2015年
18期
1-2
,共2页
妊娠%高血压%HELLP综合征%血小板
妊娠%高血壓%HELLP綜閤徵%血小闆
임신%고혈압%HELLP종합정%혈소판
Pregnancy%Hypertension%HELLP syndrome%Platelet
目的 探讨分析重度妊娠高血压并发HEL.LP综合征的发病率、诊断、治疗及预后.方法 回顾性分析18例重度妊娠高血压合并HELLP综合征患者的病例资料,将患者按照血小板计数分型分为两组:Ⅰ级HELLP综合征组(11例)与Ⅱ级HELLP综合征组(7例).对两组患者的各项指标变化情况以及母婴并发症发生情况进行分析.结果 Ⅰ级HELLP综合征组门冬氯酸氨基转移酶、乳酸脱氢酶高于Ⅱ级HELLP综合征组,血小板计数低于Ⅱ级HELLP综合征组,差异均有统计学意义(P＜0.05).Ⅰ级HELLP综合征组孕产妇发生弥散性血管内凝血的概率及围生儿发生胎儿宫内发育迟缓的概率均高于Ⅱ级HELLP综合征组,差异均有统计学意义(P＜0.05).18例患者中1例死于产后HELLP综合征,围生儿死亡3例.结论 HELLP综合征是重度妊娠高血压疾病的一种严重威胁母婴安全的并发症,尤其是Ⅰ级HELLP综合征,及早发现并应用糖皮质激素治疗,终止妊娠是治疗最有效的措施,可以降低母婴死亡率.
目的 探討分析重度妊娠高血壓併髮HEL.LP綜閤徵的髮病率、診斷、治療及預後.方法 迴顧性分析18例重度妊娠高血壓閤併HELLP綜閤徵患者的病例資料,將患者按照血小闆計數分型分為兩組:Ⅰ級HELLP綜閤徵組(11例)與Ⅱ級HELLP綜閤徵組(7例).對兩組患者的各項指標變化情況以及母嬰併髮癥髮生情況進行分析.結果 Ⅰ級HELLP綜閤徵組門鼕氯痠氨基轉移酶、乳痠脫氫酶高于Ⅱ級HELLP綜閤徵組,血小闆計數低于Ⅱ級HELLP綜閤徵組,差異均有統計學意義(P＜0.05).Ⅰ級HELLP綜閤徵組孕產婦髮生瀰散性血管內凝血的概率及圍生兒髮生胎兒宮內髮育遲緩的概率均高于Ⅱ級HELLP綜閤徵組,差異均有統計學意義(P＜0.05).18例患者中1例死于產後HELLP綜閤徵,圍生兒死亡3例.結論 HELLP綜閤徵是重度妊娠高血壓疾病的一種嚴重威脅母嬰安全的併髮癥,尤其是Ⅰ級HELLP綜閤徵,及早髮現併應用糖皮質激素治療,終止妊娠是治療最有效的措施,可以降低母嬰死亡率.
목적 탐토분석중도임신고혈압병발HEL.LP종합정적발병솔、진단、치료급예후.방법 회고성분석18례중도임신고혈압합병HELLP종합정환자적병례자료,장환자안조혈소판계수분형분위량조:Ⅰ급HELLP종합정조(11례)여Ⅱ급HELLP종합정조(7례).대량조환자적각항지표변화정황이급모영병발증발생정황진행분석.결과 Ⅰ급HELLP종합정조문동록산안기전이매、유산탈경매고우Ⅱ급HELLP종합정조,혈소판계수저우Ⅱ급HELLP종합정조,차이균유통계학의의(P＜0.05).Ⅰ급HELLP종합정조잉산부발생미산성혈관내응혈적개솔급위생인발생태인궁내발육지완적개솔균고우Ⅱ급HELLP종합정조,차이균유통계학의의(P＜0.05).18례환자중1례사우산후HELLP종합정,위생인사망3례.결론 HELLP종합정시중도임신고혈압질병적일충엄중위협모영안전적병발증,우기시Ⅰ급HELLP종합정,급조발현병응용당피질격소치료,종지임신시치료최유효적조시,가이강저모영사망솔.
Objective To investigate the incidence,diagnosis,treatment and prognosis of severe pregnancy-induced hypertension combined with HELLP syndrome.Methods The clinical data of 18 patients with severe pregnancy-induced hypertension combined with HELLP syndrome were retrospectively analyzed,and these patients were divided into two groups according to platelet count type,type Ⅰ HELLP syndrome group (11 cases) and type Ⅱ HELLP syndrome group (7 cases).Indicators changes in the two groups of patients and occurrence of maternal complications were analyzed.Resuits AST and LDH in type Ⅰ HELLP syndrome group was higher than that in type Ⅱ HELLP syndrome group,while PLT was less than that in type Ⅱ HELLP syndrome group,and differences were significant(P ＜0.05).The incidences of DIC and FGR were higher in type Ⅰ HELLP syndrome group,there were significant differences(P ＜0.05).One case died of postpartum HELLP syndrome and 3 cases died in perinatal period during the 18 cases.Conclusions HELLP syndrome is a serious complication of severe pregnancy-induced hypertension threatening the safety of maternal,specially in patients with type Ⅰ HELLP syndrome.The most effective treatment are early detection,treatment of glucocorticoid and termination of pregnancy,which can reduce the mortality of maternal and child.
