中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2015年
18期
46-47
,共2页
电针%变应性鼻炎%大鼠%白细胞介素-4%肿瘤坏死因子-γ
電針%變應性鼻炎%大鼠%白細胞介素-4%腫瘤壞死因子-γ
전침%변응성비염%대서%백세포개소-4%종류배사인자-γ
Electroacupuncture%Allergic rhinitis%Rat%Interleukin-4%Tumor necrosis factor-γ
目的 探讨电针对变应性鼻炎大鼠模型外周血白细胞介素-4(IL-4)和肿瘤坏死因子-y(TNF-γ)的影响.方法 将60只健康大鼠随机分成四组:正常对照组、模型组、丙酸氟替卡松治疗组及电针治疗组.通过卵蛋白注射及其鼻黏膜刺激法制备变应性鼻炎模型.治疗10 d后,分别测定各组血清IgE、IL-4、TNF-γ含量并行组间对比.结果 与模型组对比,电针治疗组血清IgE及IL-4明显降低、TNF-y明显升高(P＜0.05),且与丙酸氟替卡松治疗组比较差异有统计学意义(P＜0.05).结论 电针可以降低IL-4水平,增加TNF-γ水平,进而起到一定的治疗作用.
目的 探討電針對變應性鼻炎大鼠模型外週血白細胞介素-4(IL-4)和腫瘤壞死因子-y(TNF-γ)的影響.方法 將60隻健康大鼠隨機分成四組:正常對照組、模型組、丙痠氟替卡鬆治療組及電針治療組.通過卵蛋白註射及其鼻黏膜刺激法製備變應性鼻炎模型.治療10 d後,分彆測定各組血清IgE、IL-4、TNF-γ含量併行組間對比.結果 與模型組對比,電針治療組血清IgE及IL-4明顯降低、TNF-y明顯升高(P＜0.05),且與丙痠氟替卡鬆治療組比較差異有統計學意義(P＜0.05).結論 電針可以降低IL-4水平,增加TNF-γ水平,進而起到一定的治療作用.
목적 탐토전침대변응성비염대서모형외주혈백세포개소-4(IL-4)화종류배사인자-y(TNF-γ)적영향.방법 장60지건강대서수궤분성사조:정상대조조、모형조、병산불체잡송치료조급전침치료조.통과란단백주사급기비점막자격법제비변응성비염모형.치료10 d후,분별측정각조혈청IgE、IL-4、TNF-γ함량병행조간대비.결과 여모형조대비,전침치료조혈청IgE급IL-4명현강저、TNF-y명현승고(P＜0.05),차여병산불체잡송치료조비교차이유통계학의의(P＜0.05).결론 전침가이강저IL-4수평,증가TNF-γ수평,진이기도일정적치료작용.
Objective To investigate the effect of electroacupuncture on interleukin-4 (IL-4) and tumor necrosis factor-γ(TNF-γ) in model of rats with allergic rhinitis (AR).Methods Sixty rats were randomly divided into control group,model group,western medicine group and electroacupuncture group.The rats were sensitized by ovalbumin.The levels of IgE,IL-4,TNF-γwere measured and compared among the four groups.Results The level of IL-4 in electroacupuncture group was significantly lower than that in model group and westem medicine group (P ＜ 0.05);The level of TNF-γ in electroacupuncture group was significantly higher than that in model group and western medicine group (P ＜ 0.05).Condusions Electroacupuncture can reduce the level of IL-4 and increase the TNF-γ content in serum,thus play a therapeutic effect.
