CAJ | 학술논문

目的：对比完全腹腔镜全胃切除治疗家族性胃癌与普通胃癌的预后疗效。方法2012年8月—2014年8月选择在我院进行诊治的普通胃癌患者60例作为对照组，同期选择收治的家族性胃癌患者40例作为观察组，都给予腹腔镜辅助下根治性全胃切除术。结果两组手术时间、术中出血量、术后排气时间对比差异无统计学意义（P＞0．05），但观察组的术后住院时间与淋巴结清扫个数明显多于对照组（ P＜0．001）。观察组术后发生并发症如腹腔感染、肺部感染、肠梗阻、手术吻合处出血等情况均明显少于对照组（P＜0．001）。术后1个月进行调查，观察组的吞咽困难、疼痛、焦虑、躯体外观和口干等评分明显高于对照组（P＜0．001）。结论家族性胃癌具有独特的临床病理特点，相对于普通胃癌，完全腹腔镜全胃切除治疗家族性胃癌需要清扫更多的淋巴结，能造成更多的并发症，对于患者生活质量也有一定的影响。
목적：대비완전복강경전위절제치료가족성위암여보통위암적예후료효。방법2012년8월—2014년8월선택재아원진행진치적보통위암환자60례작위대조조，동기선택수치적가족성위암환자40례작위관찰조，도급여복강경보조하근치성전위절제술。결과량조수술시간、술중출혈량、술후배기시간대비차이무통계학의의（P＞0．05），단관찰조적술후주원시간여림파결청소개수명현다우대조조（ P＜0．001）。관찰조술후발생병발증여복강감염、폐부감염、장경조、수술문합처출혈등정황균명현소우대조조（P＜0．001）。술후1개월진행조사，관찰조적탄인곤난、동통、초필、구체외관화구간등평분명현고우대조조（P＜0．001）。결론가족성위암구유독특적림상병리특점，상대우보통위암，완전복강경전위절제치료가족성위암수요청소경다적림파결，능조성경다적병발증，대우환자생활질량야유일정적영향。
Objective To compare the prognosis efficacy between total laparoscopic gastrectomy and or-dinary gastric cancer for familial gastric cancer.Methods The selected 60 patients with ordinary gastric cancer from August 2012 to 2014 in our hospital as the control group,the same period in familial gastric cancer of 40 pa-tients were chosen as control group.All patients were performed by total laparoscopic gastrectomy.Results The operative time,blood loss,postoperative discharge time compared in the two groups were showed no significant differences.However,the postoperative hospital stayed in the observation group and the number of lymph nodes were significantly longer more than the control group( P<0.001) .The postoperative pulmonary infection,intesti-nal obstruction,abdominal infection,anastomotic leakage,anastomotic bleeding and other complications in the ob-servation group were significantly lower than in the control group( P<0.001) .After the investigation,the dyspha-gia,pain,anxiety,physical appearance,dry mouth scores in the observation group were significantly higher(P<0. 001).Conclusion Familial gastric cancer has unique clinical and pathological features,Compared to ordinary stomach,the total laparoscopic gastrectomy treatment of familial gastric cancer need more lymph nodes dissection, it can cause more complications,it has some impacts on the quality of life for patients.