CAJ | 학술논문

目的：总结颅内静脉窦血栓形成(CVST)的临床特点,提高对该病的早期诊断和治疗水平。方法分析2例 CVST 的临床特点、影像学和实验室检查资料及治疗效果。结果2例患者均为男性,分别为48岁、63岁。1例有眼球感染,另1例无明显诱因。2例均有头痛等神经系统症状,病情迅速加重。2例头颅 CT 检查均出现两侧大脑半球肿胀,局部出血灶和明显占位效应,1例数字减影血管造影(DSA)示局部静脉、静脉窦不显影。1例腰椎穿刺颅内压升高,呈血性脑脊液。2例患者经抗凝等综合治疗均获得良好疗效。结论 CVST 以头痛等症状为主要表现,病情进展迅猛,头颅 CT 表现为两侧大脑半球肿胀,局部出血,占位效应明显,早期诊断及治疗效果好。
목적：총결로내정맥두혈전형성(CVST)적림상특점,제고대해병적조기진단화치료수평。방법분석2례 CVST 적림상특점、영상학화실험실검사자료급치료효과。결과2례환자균위남성,분별위48세、63세。1례유안구감염,령1례무명현유인。2례균유두통등신경계통증상,병정신속가중。2례두로 CT 검사균출현량측대뇌반구종창,국부출혈조화명현점위효응,1례수자감영혈관조영(DSA)시국부정맥、정맥두불현영。1례요추천자로내압승고,정혈성뇌척액。2례환자경항응등종합치료균획득량호료효。결론 CVST 이두통등증상위주요표현,병정진전신맹,두로 CT 표현위량측대뇌반구종창,국부출혈,점위효응명현,조기진단급치료효과호。
Objective To summarize the clinical features of intracranial venous sinus thrombosis (CVST),as well as to improve the early diagnosis and treatment.Methods The clinical characteristics,imaging,laboratory examination data and the treatment effect of CVST were retrospectively analyzed.Results The two patients were male,28 and 30 years old.One patient with eye infection,and no obvious cause in the other one.Headache and other neurological symptoms were found in both cases,and the patients'condition rapidly worsened.Head CT scan showed cerebral hemispheric swelling in both cases,local hemorrhage and obvious space occupying effect.Partial vein and venous sinuses of one casewere not visualized with DSA.Lumbar puncture identified increased intracranial pressure, and bloody cerebrospinal fluid was obtained.Two patients were treated well after anticoagulant and comprehensive treatment.Conclusion CVST was characterized by headache and other neurological symptoms,and the disease developed rapidly.Cerebral hemispheric swelling,local bleeding and obvious space occupying effect were found by head CT.It can be treated well in the early stage of diagnosis.