CAJ | 학술논문

以显齿蛇葡萄叶中含量丰富且易于提取的二氢杨梅素( DMY)为原料,半合成得到杨梅素( MYR)。产物经FI-IR,1H NMR和13C NMR结构鉴定,确认是杨梅素。在单因素试验的基础上,选取吡啶体积分数、料液比和反应温度为影响因子,以 MYR 得率作为响应值,进行响应面分析(RSM)。结果表明,MYR的最佳合成工艺参数为：吡啶体积分数66.6%、反应温度90.4℃、料液比值为20.88时MYR得率为76.63%,与预测值76.48%的相对误差为0.19%。
이현치사포도협중함량봉부차역우제취적이경양매소( DMY)위원료,반합성득도양매소( MYR)。산물경FI-IR,1H NMR화13C NMR결구감정,학인시양매소。재단인소시험적기출상,선취필정체적분수、료액비화반응온도위영향인자,이 MYR 득솔작위향응치,진행향응면분석(RSM)。결과표명,MYR적최가합성공예삼수위：필정체적분수66.6%、반응온도90.4℃、료액비치위20.88시MYR득솔위76.63%,여예측치76.48%적상대오차위0.19%。
Dihydromyricetion( DMY) , which was abundant and easily extracted from the leaves of Ampelopsis grossedentata, was used as the semisynthetic sources for myricetin( MYR) . The structure of MYR was characterized by IR, 1H NMR and 13C NMR. Based on the results of the single factor experiments, response surface methodology( RSM) was applied to further optimize the synthesis conditions with pyridine volume fraction, and temperature, solid-liquid-ratio as the impact factors and MYR yield as the response value. The most suitable synthesis conditions of MYR were determined as follows: pyridine volume fraction 66. 6%, temperature 90. 4 ℃ and solid-liquid ratio 20. 88(g∶L). The MYR yield was 76. 63%, and the relative error with the predictive value of 76. 48% was 0. 19%.