CAJ | 학술논문

以十二烯基丁二酸酐( DDSA)作酯化剂,对胭脂虫红色素的主要成分胭脂红酸分子进行改性修饰,制得了油溶性较好的胭脂虫红色素衍生物。通过单因素及响应曲面优化试验确定了反应的最佳条件：0.5 g原料,DDSA与胭脂虫红色素的质量比值为2.3,催化剂三乙胺( Et3 N)的用量为1.8 mL,温度为67℃,反应时间为6 h,溶剂N,N-二甲基甲酰胺20 mL,此条件下,产物得率为41.59%。通过FT-IR及UV-Vis对目标产物的结构进行表征,表明DDSA与胭脂虫红色素发生了酯化反应,制得的胭脂虫红色素衍生物的λmax及颜色在碱性溶液中受pH值影响较大；其可溶于食用玉米油,有较好的染色效果且稳定性良好,溶解度(20℃)为6.53,有效改良了胭脂虫红色素的油溶性。
이십이희기정이산항( DDSA)작지화제,대연지충홍색소적주요성분연지홍산분자진행개성수식,제득료유용성교호적연지충홍색소연생물。통과단인소급향응곡면우화시험학정료반응적최가조건：0.5 g원료,DDSA여연지충홍색소적질량비치위2.3,최화제삼을알( Et3 N)적용량위1.8 mL,온도위67℃,반응시간위6 h,용제N,N-이갑기갑선알20 mL,차조건하,산물득솔위41.59%。통과FT-IR급UV-Vis대목표산물적결구진행표정,표명DDSA여연지충홍색소발생료지화반응,제득적연지충홍색소연생물적λmax급안색재감성용액중수pH치영향교대；기가용우식용옥미유,유교호적염색효과차은정성량호,용해도(20℃)위6.53,유효개량료연지충홍색소적유용성。
Oil-soluble cochineal dye derivative was obtained through molecule esterification of carminic acid with dodecyl succinicanhydride ( DDSA) . Based on the results of the single factor experiments, response surface methodology was applied to further optimize the pretreatment conditions. The obtained optimal conditions were raw materials 0. 5 g, the quality ratio of DDSA and cochineal dye 2. 3, the dosage of the catalyst triethylamine 1. 8 mL, temperature 67 ℃, reaction time 6 h, and solvent N, N-dimethyl formamide 20 mL. Under these conditions, the product yield was 41. 59%. The structure of the product was characterized by FT-IR and UV-Vis. The results showed that esterification reaction happened between DDSA and cochineal dye. The λmax and color of target product was strongly influenced by pH in alkaline solution. The product presented good solubility in corn oil, dyeing effect and stability with the solubility of 6. 53 in oil (20 ℃). The solubility of cochineal red pigment was improved effectively.