国际输血及血液学杂志
國際輸血及血液學雜誌
국제수혈급혈액학잡지
INTERNATIONAL JOURNAL OF BLOOD TRANSFUSION AND HEMATOLOGY
2015年
4期
300-302
,共3页
血液成分输血%血小板输注%单采血小板%代谢%血小板功能试验%血液保存%临床输血
血液成分輸血%血小闆輸註%單採血小闆%代謝%血小闆功能試驗%血液保存%臨床輸血
혈액성분수혈%혈소판수주%단채혈소판%대사%혈소판공능시험%혈액보존%림상수혈
Blood component transfusion%Platelets transfusion%Apheresis platelets%Metabolism%Platelet function tests%Blood preservation%Clinical blood transfusion
目的 探讨单采血小板的储存时间对其代谢功能的影响.方法 选择四川自贡市中心血站向医院提供的新鲜单采血小板悬液30袋,每袋包含1治疗量血小板,每袋血小板含量为(2.5～3.0)×1011/袋为研究对象.将其编号后按照数字表法随机平均分为:保存1d组、保存3d组及保存5d组,每组各为10袋.3组分别在保存时间为1,3及5d时取样,检测乳酸、乳酸脱氢酶(LDH)、葡萄糖含量和pH值等代谢功能相关指标,并进行统计学分析.结果 随着保存时间延长,单采血小板悬液的pH值及葡萄糖含量呈逐渐下降趋势,差异有统计学意义(P＜0.05);而LDH及乳酸含量呈逐渐升高趋势,差异亦有统计学意义(P＜0.05).结论 单采血小板悬液在22℃保存5d内,其代谢功能发生明显变化.临床输注的单采血小板在储存时间内,其储存时间越短,质量越好.
目的 探討單採血小闆的儲存時間對其代謝功能的影響.方法 選擇四川自貢市中心血站嚮醫院提供的新鮮單採血小闆懸液30袋,每袋包含1治療量血小闆,每袋血小闆含量為(2.5～3.0)×1011/袋為研究對象.將其編號後按照數字錶法隨機平均分為:保存1d組、保存3d組及保存5d組,每組各為10袋.3組分彆在保存時間為1,3及5d時取樣,檢測乳痠、乳痠脫氫酶(LDH)、葡萄糖含量和pH值等代謝功能相關指標,併進行統計學分析.結果 隨著保存時間延長,單採血小闆懸液的pH值及葡萄糖含量呈逐漸下降趨勢,差異有統計學意義(P＜0.05);而LDH及乳痠含量呈逐漸升高趨勢,差異亦有統計學意義(P＜0.05).結論 單採血小闆懸液在22℃保存5d內,其代謝功能髮生明顯變化.臨床輸註的單採血小闆在儲存時間內,其儲存時間越短,質量越好.
목적 탐토단채혈소판적저존시간대기대사공능적영향.방법 선택사천자공시중심혈참향의원제공적신선단채혈소판현액30대,매대포함1치료량혈소판,매대혈소판함량위(2.5～3.0)×1011/대위연구대상.장기편호후안조수자표법수궤평균분위:보존1d조、보존3d조급보존5d조,매조각위10대.3조분별재보존시간위1,3급5d시취양,검측유산、유산탈경매(LDH)、포도당함량화pH치등대사공능상관지표,병진행통계학분석.결과 수착보존시간연장,단채혈소판현액적pH치급포도당함량정축점하강추세,차이유통계학의의(P＜0.05);이LDH급유산함량정축점승고추세,차이역유통계학의의(P＜0.05).결론 단채혈소판현액재22℃보존5d내,기대사공능발생명현변화.림상수주적단채혈소판재저존시간내,기저존시간월단,질량월호.
Objective To study the effect of storage time on metabolic function of apheresis platelets.Methods Selected a total of 30 bags of apheresis platelets which were collected from 30 cases of voluntary blood donors as research subjects.The volume of each bag of apheresis platelets was one therapeutic dose,and platelet count was (2.5～3.0) × 1011/L.All of 30 bags of apheresis platelets would been stored in storage tank for 5 days at 22 ℃.The 30 bags of apheresis platelets were randomly divided into storage for 1 day group (n=10),storage for 3 days group and storage for 5 days group (n=10) equally by digital table method after being numbered.Content of lactic acid,lactate dehydrogenase (LDH),content of glucose and pH value were detected among 3 groups.Relationship of the metabolic function of apheresis platelets and storage time were analyzed by statistical method.Results The longer the storage duration time of apheresis platelets was,the lower of pH values and content of glucose in apheresis platelets were,and there were significant differences among 3 groups (P＜0.05).At the same time,contents of LDH and lactic acid in apheresis platelets were gradually increased,and there also were significant differences among 3 groups (P＜0.05).Conclusions There are marked changes for metabolic function of apheresis platelets in storage of 5 days at 22 ℃.The shorter the storage duration time of apheresis platelets is,the better quality of apheresis platelets is.
