CAJ | 학술논문

世界卫生组织(WHO)“造血和淋巴系统肿瘤分类(2008年版)”中,将“嗜酸性粒细胞增多及血小板衍生的生长因子受体(PDGFR)α,β或成纤维生长因子受体(FGFR)1异常的髓系、淋巴系肿瘤(MLN-eo)”作为一类疾病单独列出.2011年,维也纳医学院组织的由多学科专家参与的“嗜酸性粒细胞相关疾病工作会议”结合既往诊断标准,就嗜酸性粒细胞增多相关疾病的诊断和分类进行了更新,但迄今为止,嗜酸性粒细胞增多相关疾病的分类、命名仍然比较混乱.笔者拟就近年嗜酸性粒细胞增多相关疾病文献进行复习,对嗜酸性粒细胞增多相关疾病,特别是克隆性嗜酸性粒细胞增多相关疾病的分类和诊疗进展进行综述.
세계위생조직(WHO)“조혈화림파계통종류분류(2008년판)”중,장“기산성립세포증다급혈소판연생적생장인자수체(PDGFR)α,β혹성섬유생장인자수체(FGFR)1이상적수계、림파계종류(MLN-eo)”작위일류질병단독렬출.2011년,유야납의학원조직적유다학과전가삼여적“기산성립세포상관질병공작회의”결합기왕진단표준,취기산성립세포증다상관질병적진단화분류진행료경신,단흘금위지,기산성립세포증다상관질병적분류、명명잉연비교혼란.필자의취근년기산성립세포증다상관질병문헌진행복습,대기산성립세포증다상관질병,특별시극륭성기산성립세포증다상관질병적분류화진료진전진행종술.
In the 2008 World Health Organization (WHO) classification of tumors of heamatopoietic and lymphoid tissues,"myeloid and lymphoid neoplasms with eosinophilia and abnormalities of plateletderived growth factor receptor (PDGFR)α,PDGFRβ or fibroblast growth factor receptor (FGFR)1 (MLN-eo)" is listed as an individual disease.In 2011,working conference on eosinophil disorders and syndromes was organized to update and refine the criteria and definitions for eosinophilic disorders and to merge prior classifications in a contemporary multidisciplinary schema.But the nomination and classification of diseases with eosinophilia is still chaos so far,to some extent.In this review,we will sum up the classification and treatment of the diseases,and mainly expound the diagnosis and treatment of the clonal diseases with eosinophilia.