CAJ | 학술논문

5-氨基间苯二甲酸是有机合成的重要中间体。以5-硝基间苯二甲酸为原料，首先用烯丙基溴对羧基进行保护，然后将硝基进行还原，最后去掉保护基团。通过此方法很容易合成目标化合物，相对步骤较多，很容易分离提纯，但是对最终的产率影响不大。
5-안기간분이갑산시유궤합성적중요중간체。이5-초기간분이갑산위원료，수선용희병기추대최기진행보호，연후장초기진행환원，최후거도보호기단。통과차방법흔용역합성목표화합물，상대보취교다，흔용역분리제순，단시대최종적산솔영향불대。
5-Aminoisophthalic acid is an important intermediate of organic synthesis. In this paper, taking 5-nitroisophthalic acid as raw material, allyl bromide was used to protect carboxyl, 5-aminoisophthalic acid was synthesized, and then the protective group was removed. This method that can easy synthesize the target compound, relative steps are more, the product is easy separated and purified.