CAJ | 학술논문

建立了一个三维光热模型，应用该模型分别研究了红外激光脉冲在人耳蜗和动物耳蜗内由于激光吸收引起的温度变化。采用有限元方法，数值模拟了耳蜗内温度在空间和时域的变化。研究发现尽管激光吸收引起了一定的温度升高，但是可以通过调节激光脉冲参数比如激光功率和重复频率对温度变化进行控制。通过对比相同参数的激光脉冲在豚鼠耳蜗内和人耳蜗内引起的温度变化，发现动物耳蜗内温度升高较明显。因此从激光热效应的角度看，动物实验能有效帮助合理选择激光在人耳蜗内的安全参数。
건립료일개삼유광열모형，응용해모형분별연구료홍외격광맥충재인이와화동물이와내유우격광흡수인기적온도변화。채용유한원방법，수치모의료이와내온도재공간화시역적변화。연구발현진관격광흡수인기료일정적온도승고，단시가이통과조절격광맥충삼수비여격광공솔화중복빈솔대온도변화진행공제。통과대비상동삼수적격광맥충재돈서이와내화인이와내인기적온도변화，발현동물이와내온도승고교명현。인차종격광열효응적각도간，동물실험능유효방조합리선택격광재인이와내적안전삼수。
A simplified 3D model has been developed to simulate heating effects in human cochlea and guinea pig cochlea when infrared laser pulses are applied to stimulate their ganglion neurons. It simplifies the spiral structure of the cochlea by a rota-tional symmetry with the 3D structure of the cochlea, and applies the finite element method to solve the heat equation and allows de-tailed investigation of the temperature rise in spatial and temporal domains. The numerical results show that the temperature rises within cochleae can be controlled in a safe range by adjusting the laser power and repetition rate. Additionally, the results show that the heating in guinea pig cochlea is higher than that in human cochlea because of the effect of the boundary conditions. It indicates that experiments with laser safety performed on guinea pig cochlea could be a good guidance for studying laser safety in human.