中华胰腺病杂志
中華胰腺病雜誌
중화이선병잡지
CHINESE JOURNAL OF PANCREATOLOGY
2015年
4期
242-246
,共5页
王铁功%詹茜%刘芳%陈录广%邵成伟%陆建平
王鐵功%詹茜%劉芳%陳錄廣%邵成偉%陸建平
왕철공%첨천%류방%진록엄%소성위%륙건평
胰腺%神经内分泌肿瘤%体层摄影术,X线计算机%诊断
胰腺%神經內分泌腫瘤%體層攝影術,X線計算機%診斷
이선%신경내분비종류%체층섭영술,X선계산궤%진단
Pancreas%Neuroendocrine tumor%Tomography,X-ray computed%Diagnosis
目的 分析胰腺神经内分泌肿瘤(PNETs)的良恶性CT征象,提高对该病的定性诊断水平.方法 回顾性分析96例经病理证实的PNETs患者临床资料及CT图像,分析肿瘤的大小、形态、位置、内部结构、钙化、分隔、胰胆管扩张及CT值.结果 依据病理诊断标准,96例患者中良性40例,共41枚病灶,恶性56例,共59枚病灶.恶性组瘤体直径显著大于良性组(中位直径6.0 cm比2.2 cm),瘤块形态多不规则,以囊实性为主,可出现斑点状、弧线状、团块状钙化,胰胆管轻中度均匀扩张,两组差异均有统计学意义(P值均<0.05),而肿瘤部位、瘤内有无分隔的差异无统计学意义.45.76% (27/59)的恶性肿瘤在动脉期达到强化峰值,44.07% (26/59)在静脉期达到强化峰值;68.29% (28/41)良性肿瘤在动脉期达到强化峰值,31.71%(13/41)在静脉期达到强化峰值.恶性组在CT平扫及增强动脉期、静脉期、平衡期的CT值分别为(39.02±7.53)、(121.20±54.73)、(125.25 ±40.77)、(101.41 ±28.68) Hu;良性组分别为(41.49±8.59)、(144.73±53.95)、(157.05±44.72)、(121.02±29.80)Hu.恶性肿瘤在平扫时与良性肿瘤的CT值差异无统计学意义,而在增强期的CT值显著低于良性肿瘤,差异有统计学意义(P值均<0.05).结论 肿瘤最大径≥3.0 cm、形态不规则、有囊变坏死、钙化、胰胆管扩张等征象高度提示恶性,恶性肿瘤在增强扫描的动脉期、静脉期及平衡期的强化程度普遍低于良性肿瘤.
目的 分析胰腺神經內分泌腫瘤(PNETs)的良噁性CT徵象,提高對該病的定性診斷水平.方法 迴顧性分析96例經病理證實的PNETs患者臨床資料及CT圖像,分析腫瘤的大小、形態、位置、內部結構、鈣化、分隔、胰膽管擴張及CT值.結果 依據病理診斷標準,96例患者中良性40例,共41枚病竈,噁性56例,共59枚病竈.噁性組瘤體直徑顯著大于良性組(中位直徑6.0 cm比2.2 cm),瘤塊形態多不規則,以囊實性為主,可齣現斑點狀、弧線狀、糰塊狀鈣化,胰膽管輕中度均勻擴張,兩組差異均有統計學意義(P值均<0.05),而腫瘤部位、瘤內有無分隔的差異無統計學意義.45.76% (27/59)的噁性腫瘤在動脈期達到彊化峰值,44.07% (26/59)在靜脈期達到彊化峰值;68.29% (28/41)良性腫瘤在動脈期達到彊化峰值,31.71%(13/41)在靜脈期達到彊化峰值.噁性組在CT平掃及增彊動脈期、靜脈期、平衡期的CT值分彆為(39.02±7.53)、(121.20±54.73)、(125.25 ±40.77)、(101.41 ±28.68) Hu;良性組分彆為(41.49±8.59)、(144.73±53.95)、(157.05±44.72)、(121.02±29.80)Hu.噁性腫瘤在平掃時與良性腫瘤的CT值差異無統計學意義,而在增彊期的CT值顯著低于良性腫瘤,差異有統計學意義(P值均<0.05).結論 腫瘤最大徑≥3.0 cm、形態不規則、有囊變壞死、鈣化、胰膽管擴張等徵象高度提示噁性,噁性腫瘤在增彊掃描的動脈期、靜脈期及平衡期的彊化程度普遍低于良性腫瘤.
목적 분석이선신경내분비종류(PNETs)적량악성CT정상,제고대해병적정성진단수평.방법 회고성분석96례경병리증실적PNETs환자림상자료급CT도상,분석종류적대소、형태、위치、내부결구、개화、분격、이담관확장급CT치.결과 의거병리진단표준,96례환자중량성40례,공41매병조,악성56례,공59매병조.악성조류체직경현저대우량성조(중위직경6.0 cm비2.2 cm),류괴형태다불규칙,이낭실성위주,가출현반점상、호선상、단괴상개화,이담관경중도균균확장,량조차이균유통계학의의(P치균<0.05),이종류부위、류내유무분격적차이무통계학의의.45.76% (27/59)적악성종류재동맥기체도강화봉치,44.07% (26/59)재정맥기체도강화봉치;68.29% (28/41)량성종류재동맥기체도강화봉치,31.71%(13/41)재정맥기체도강화봉치.악성조재CT평소급증강동맥기、정맥기、평형기적CT치분별위(39.02±7.53)、(121.20±54.73)、(125.25 ±40.77)、(101.41 ±28.68) Hu;량성조분별위(41.49±8.59)、(144.73±53.95)、(157.05±44.72)、(121.02±29.80)Hu.악성종류재평소시여량성종류적CT치차이무통계학의의,이재증강기적CT치현저저우량성종류,차이유통계학의의(P치균<0.05).결론 종류최대경≥3.0 cm、형태불규칙、유낭변배사、개화、이담관확장등정상고도제시악성,악성종류재증강소묘적동맥기、정맥기급평형기적강화정도보편저우량성종류.
Objective To explore the CT findings of benign and malignant pancreatic neuroendocrine tumors and improve its diagnostic accuracy.Methods The clinical information and enhanced CT findings of 96 cases with pathologically-proved pancreatic neuroendocrine tumors were retrospectively reviewed.The CT findings were evaluated by several factors,which included tumor size,morphology,location,internal composition,calcification,separation,bile duct and pancreatic duct dilation and CT value.Results All cases were divided into benign or malignant according to pathological grades,and benign group involved 40 cases with 41 lesions,while malignant group involved 56 cases with 59 lesions.The size of malignant lesions was significantly larger than that of benign lesions (median size 6.0 cm vs 2.2 cm),the shape of the lesions was irregular,and was mainly cystic solid,and mottling,curve shape,clumps calcification was present,then the bile duct and pancreatic duct was mild to moderately dilated,and the difference between the two groups was statistically significant (P <0.05).But the difference of tumor location,separation was not significant.45.76% (27/59) of the malignant lesions reached the peak value in arterial phase,and 44.07% (26/59) reached the peak value in venous phase;while 68.29% (28/41) of the benign lesions reached the peak value in arterial phase,and 31.71% (13/41) reached the peak value in venous phase.The CT values of malignant lesions in plain CT scanning,arterial phase,venous phase,balance phase were (39.02 ±7.53),(121.20 ± 54.73),(125.25 ± 40.77),(101.41 ± 28.68) Hu,while they were (41.49 ± 8.59),(144.73 ± 53.95),(157.05 ±44.72),(121.02 ±29.80) Hu in benign group.In plain CT scanning,the difference of CT value between malignant and benign lesions was not significant;but in the enhanced phase,the CT value of malignant lesions was significantly lower than that of benign lesions,and the difference was statistically significant (P < 0.05).Conclusions The lesion with its size ≥ 3.0 cm,irregnlar morphology,cystic necrosis,calcification,pancreatic and bile duct dilatation is suggestive of malignancy tumor.The average CT values of malignant group are lower than those of the benign group in arterial,venous and balance phases.