中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2015年
17期
6-8
,共3页
李伟芳%李华%李天艺%董捷%陈素芳
李偉芳%李華%李天藝%董捷%陳素芳
리위방%리화%리천예%동첩%진소방
2型糖尿病%高血压%中老年人
2型糖尿病%高血壓%中老年人
2형당뇨병%고혈압%중노년인
Type 2 diabetes mellitus%Hypertention%Middle and elderly
目的 探讨中老年2型糖尿病(T2DM)合并高血压的相关影响因素,分析其在临床上的指导意义.方法 根据是否合并高血压将285例T2DM患者分为A组和B组,比较两组的的性别、年龄、糖尿病痛程、体质量指数(BMI)、糖尿病家族史、吸烟饮酒史等一般资料和空腹血糖(FPG)、糖化血红蛋白(HbAlc)、血脂、血尿酸(UA)、丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、超敏C-反应蛋白(hsCRP)、血小板(PLT)、血小板平均体积(MPV)、血浆凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)、纤维蛋白原(FIB)等实验室指标.结果 285例患者中T2DM合并高血压者(A组)185例(64.9％),未合并高血压者(B组)100例(35.1％),两组患者的年龄、FPG、血尿酸、TG、HDL、LDL及FIB比较差异有统计学意义(P＜0.05),A组患者年龄高于B组,且随着年龄增长,A组患病例数明显增加;A组血尿酸、HDL及FIB高于B组,而FPG、TG及LDL低于B组.采用逐步回归法进行非条件Logistic回归分析,结果显示年龄、尿酸及FIB是糖尿病合并高血压的危险因素,且水平越高者,糖尿病合并高血压的危险性增加(P＜0.05).结论 随着年龄增加,T2DM合并高血压的患病率亦升高,糖尿病合并高血压者常伴随有高尿酸血症及高凝状态.
目的 探討中老年2型糖尿病(T2DM)閤併高血壓的相關影響因素,分析其在臨床上的指導意義.方法 根據是否閤併高血壓將285例T2DM患者分為A組和B組,比較兩組的的性彆、年齡、糖尿病痛程、體質量指數(BMI)、糖尿病傢族史、吸煙飲酒史等一般資料和空腹血糖(FPG)、糖化血紅蛋白(HbAlc)、血脂、血尿痠(UA)、丙氨痠氨基轉移酶(ALT)、天鼕氨痠氨基轉移酶(AST)、超敏C-反應蛋白(hsCRP)、血小闆(PLT)、血小闆平均體積(MPV)、血漿凝血酶原時間(PT)、活化部分凝血酶原時間(APTT)、纖維蛋白原(FIB)等實驗室指標.結果 285例患者中T2DM閤併高血壓者(A組)185例(64.9％),未閤併高血壓者(B組)100例(35.1％),兩組患者的年齡、FPG、血尿痠、TG、HDL、LDL及FIB比較差異有統計學意義(P＜0.05),A組患者年齡高于B組,且隨著年齡增長,A組患病例數明顯增加;A組血尿痠、HDL及FIB高于B組,而FPG、TG及LDL低于B組.採用逐步迴歸法進行非條件Logistic迴歸分析,結果顯示年齡、尿痠及FIB是糖尿病閤併高血壓的危險因素,且水平越高者,糖尿病閤併高血壓的危險性增加(P＜0.05).結論 隨著年齡增加,T2DM閤併高血壓的患病率亦升高,糖尿病閤併高血壓者常伴隨有高尿痠血癥及高凝狀態.
목적 탐토중노년2형당뇨병(T2DM)합병고혈압적상관영향인소,분석기재림상상적지도의의.방법 근거시부합병고혈압장285례T2DM환자분위A조화B조,비교량조적적성별、년령、당뇨병통정、체질량지수(BMI)、당뇨병가족사、흡연음주사등일반자료화공복혈당(FPG)、당화혈홍단백(HbAlc)、혈지、혈뇨산(UA)、병안산안기전이매(ALT)、천동안산안기전이매(AST)、초민C-반응단백(hsCRP)、혈소판(PLT)、혈소판평균체적(MPV)、혈장응혈매원시간(PT)、활화부분응혈매원시간(APTT)、섬유단백원(FIB)등실험실지표.결과 285례환자중T2DM합병고혈압자(A조)185례(64.9％),미합병고혈압자(B조)100례(35.1％),량조환자적년령、FPG、혈뇨산、TG、HDL、LDL급FIB비교차이유통계학의의(P＜0.05),A조환자년령고우B조,차수착년령증장,A조환병례수명현증가;A조혈뇨산、HDL급FIB고우B조,이FPG、TG급LDL저우B조.채용축보회귀법진행비조건Logistic회귀분석,결과현시년령、뇨산급FIB시당뇨병합병고혈압적위험인소,차수평월고자,당뇨병합병고혈압적위험성증가(P＜0.05).결론 수착년령증가,T2DM합병고혈압적환병솔역승고,당뇨병합병고혈압자상반수유고뇨산혈증급고응상태.
Objective To investigate the related factors of type 2 diabetes mellitus with hypertention,and analyze the directive significance in clinical practice.Methods According to T2DM patients with or without hypertention,these 285 subjects were divided into group A and group B.The general data including gender,age,duration of diabetes,body mass index (BMI),diabetic family history,etc and the laboratory test results including fasting plasma glucose (FPG),HbAlc,lipid,uric acid (UA),alanine aminotransferase (ALT),aspartate aminotransferase (AST),high sensitivity c-reactive protein (hsCRP),prothrombin time(PT),etc,were compared between the two groups.Results One hundred and eighty-five cases with hypertention in group A was 64.9％ and 100 cases without hypertention in group B was 35.1％ in 285 T2DM patients.There were significant differences between the two groups in age,FPG,uric acid,triglyceride (TG),high density lipoprotein-cholesterol(HDL),low density lipoprotein (LDL) and fibrinogen (FIB).The age of group A was elder than that of group B,and the patients of group A were more following the increase of age.The blood uric acid,HDL and FIB levels in group A were higher than those of group B,but FPG,TG and LDL level were lower than those in group B.Unconditional logistic stepwise regression analysis showed that age,uric acid and FIB were the risk factors of hypertention in type 2 diabetes mellitus (P ＜ 0.05).Conclusions The morbidity of T2DM combined with hypertension rised along with the increase of age.And it always combined with hyperuricemia and hypercoagulation.
